Evidence map›Paper›PMID 34341917›Full record

ArticleJournal of general internal medicine2022

Discussion and Initiation of HIV Pre-exposure Prophylaxis Were Rare Following Diagnoses of Sexually Transmitted Infections Among Veterans.

Takaaki Kobayashi, Puja Van Epps, Marissa M Maier, Lauren A Beste, Brice F Beck, Bruce Alexander, Michael E Ohl

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Takaaki KobayashiDepartment of Internal Medicine, University of Iowa, 200 Hawkins Drive, SW34 GH, Iowa City, IA, USA. Takaaki-kobayashi@uiowa.edu.ORCID 0000-0003-4751-6859
Puja Van EppsVA North East Ohio Healthcare System, Cleveland, OH, USA.
Marissa M MaierVA Portland Health Care System, Portland, OR, USA.
Lauren A BesteGeneral Medicine Service, VA Puget Sound Health Care System, Seattle, WA, USA.
Brice F BeckCenter for Access & Delivery Research and Evaluation, Iowa City VA Health Care System, Iowa City, IA, USA.
Bruce AlexanderCenter for Access & Delivery Research and Evaluation, Iowa City VA Health Care System, Iowa City, IA, USA.
Michael E OhlDepartment of Internal Medicine, University of Iowa, 200 Hawkins Drive, SW34 GH, Iowa City, IA, USA.
Iowa City VA Health Care System · USUniversity of Iowa · USOregon Health & Science University · USUniversity of Washington · USVA Northeast Ohio Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare encounters for the diagnosis and treatment of sexually transmitted infections (STIs) are common and represent an opportunity to discuss and initiate HIV pre-exposure prophylaxis (PrEP). Little is known about how frequently PrEP is discussed and initiated in association with encounters for STIs.

designRetrospective cohort and nested case-control study, matched by STI date, in national Veterans Health Administration (VHA) facilities  from January 2013 to December 2018.

participantsVeterans with a first STI diagnosis (i.e., early syphilis, gonorrhea, or chlamydia) based on ICD codes, excluding those with prior HIV diagnosis, prior PrEP use, or STI diagnosed on screening during a visit to initiate PrEP. MAIN MEASURES: Frequency of PrEP initiation within 90 days of healthcare encounter for STIs. In the case-control study, we performed a structured chart review from the initial STI-related clinical encounter and quantified frequency of PrEP discussions among matched patients who did and did not initiate PrEP in the following 90 days. KEY

resultsWe identified 23,312 patients with a first STI, of whom 90 (0.4%) started PrEP within 90 days. PrEP initiation was associated with urban residence (OR = 5.0, 95% CI 1.8-13.5), White compared to Black race (OR = 1.7, 95% CI 1.0-2.7), and syphilis diagnosis (OR = 5.7, 95% CI 3.7-8.6). Chart review revealed that discussion of PrEP was rare among people with STIs who did not subsequently start PrEP (1.1%, 95% CI 0.1-4.0). PrEP initiation was associated with documentation of sexual history (80.0% of initiators vs. 51.0% of non-initiators, p < 0.01) and discussion of PrEP (52.2% vs. 1.1%, p < 0.01) during the initial STI diagnosis encounter.

conclusionsDiscussion and initiation of PrEP were rare following healthcare encounters for STIs. Interventions are needed to improve low rates of sexual history-taking and discussion of PrEP during healthcare encounters for STIs.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexually Transmitted DiseasesSyphilisVeteransCase-Control StudiesHomosexuality, MaleHumansMaleRetrospective Studies

Identifiers

PMID34341917
PMCPMC9360206
OpenAlexW3188068538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.