Evidence map›Paper›PMID 34341883›Full record

ArticleMikrochimica acta2021

Rapid and specific detection nanoplatform of serum exosomes for prostate cancer diagnosis.

Qiaoyu Li, Yanlin Wang, Ling Ling, Liang Qiao, Hui Chen, Chuanfan Ding, Shaoning Yu

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiaoyu LiDepartment of Chemistry, Fudan University, Shanghai, 200438, China.
Yanlin WangDepartment of Chemistry, Fudan University, Shanghai, 200438, China.
Ling LingZhejiang Provincial Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, 315211, Zhejiang, China.
Liang QiaoDepartment of Chemistry, Fudan University, Shanghai, 200438, China.
Hui ChenDepartment of Chemistry, Fudan University, Shanghai, 200438, China.
Chuanfan DingZhejiang Provincial Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, 315211, Zhejiang, China. dingchuanfan@nbu.edu.cn.
Shaoning YuZhejiang Provincial Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, 315211, Zhejiang, China. yushaoning@nbu.edu.cn.ORCID http://orcid.org/0000-0002-5153-9829

Funding

National Natural Science Foundation of China 31470786the National Key Research and Development Plan of China 2018YFF0212501
6 · The paper itself

Abstract

Tumor exosomes that inherit specific molecules from their parent cells are emerging as ideal biomarkers in cancer diagnostics. Most currently available exosome isolation and detection methods are time-consuming and non-specific; thus, rapid and specific exosome detection methods are needed both clinically and in research. Here, a dual-functional platform is reported composed of reversible conjunction and "off-on" signal responses. Fe

Indexed as

ExosomesAntigens, SurfaceAptamers, NucleotideBiosensing TechniquesFluorescent DyesGlutamate Carboxypeptidase IIHumansImmobilized Nucleic AcidsLimit of DetectionMagnetite NanoparticlesMalep-DimethylaminoazobenzeneProstatic NeoplasmsRhodaminesSilicon DioxideSpectrometry, Fluorescence4-(4-dimethylaminophenylazo)benzoic acid5-carboxytetramethylrhodamine succinimidyl esterAntigens, SurfaceAptamers, NucleotideFluorescent DyesFOLH1 protein, humanGlutamate Carboxypeptidase IIImmobilized Nucleic AcidsMagnetite Nanoparticlesp-DimethylaminoazobenzeneRhodaminesSilicon DioxideTitaniumtitanium dioxideFluorescence detection; Tumor exosomesProstate cancerPSMA aptasensorTraumatogenic biopsies

Identifiers

PMID34341883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.