Evidence map›Paper›PMID 34341783›Full record

ArticleCell reports methods2021

Retrospective cell lineage reconstruction in humans by using short tandem repeats.

Liming Tao, Ofir Raz, Zipora Marx, Manjusha S Ghosh, Sandra Huber, Julia Greindl-Junghans, Tamir Biezuner, Shiran Amir, Lilach Milo, Rivka Adar and 12 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  4. Review
  5. Cell lineage tracing: Methods, applications, and challenges.Quantitative biology (Beijing, China) · 2025
    Review
  6. Article
  7. Article
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  15. Article
  16. Article
  17. Applications of Single-Cell DNA Sequencing.Annual review of genomics and human genetics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 3 countries.

Liming TaoDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Ofir RazDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Zipora MarxDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Manjusha S GhoshExperimental Medicine and Therapy Research, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Sandra HuberExperimental Medicine and Therapy Research, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Julia Greindl-JunghansExperimental Medicine and Therapy Research, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Tamir BiezunerDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Shiran AmirDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Lilach MiloDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Rivka AdarDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Ron LevyDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Amos OnnDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Noa Chapal-IlaniDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Veronika BermanDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Asaf Ben ArieDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Guy RomDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Barak OronDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Ruth HalabanDepartment of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA.
Zbigniew T CzyzExperimental Medicine and Therapy Research, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Melanie Werner-KleinExperimental Medicine and Therapy Research, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Christoph A KleinExperimental Medicine and Therapy Research, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.
Ehud ShapiroDepartment of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 761001, Israel.
Weizmann Institute of Science · ILUniversity of Regensburg · DEYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale SPORE in Skin CancerP50CA121974 · NCI · YALE UNIVERSITY · PI RUTH HALABAN · 2006 to 2026
$43.9M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P50 CA121974
6 · The paper itself

Abstract

Cell lineage analysis aims to uncover the developmental history of an organism back to its cell of origin. Recently, novel

Indexed as

Gene EditingMicrosatellite RepeatsAnimalsCell LineageHumansMutationRetrospective Studiescell lineage reconstructionmolecular inversion probesshort tandem repeatssingle-cell genomics

Identifiers

PMID34341783
PMCPMC8313865
OpenAlexW3184407227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.