Evidence map›Paper›PMID 34341776›Full record

ArticleMetabolism open2021

A systematic review on the effects of

Monique Aucoin, Valentina Cardozo, Meagan D McLaren, Anna Garber, Daniella Remy, Joy Baker, Adam Gratton, Mohammed Ali Kala, Sasha Monteiro, Cara Warder and 2 more

Open access · goldAbstract read
In one paragraph

Article in Metabolism open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Immune system evaluation of Echinacea Purpurea root extract in female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) rats.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Effects ofMolecules (Basel, Switzerland) · 2025
    Article
  7. Plants (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Plants (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Response to Dr. DF Naude.Explore (New York, N.Y.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 3 countries.

Monique AucoinCanadian College of Naturopathic Medicine, Canada.
Valentina CardozoCanadian College of Naturopathic Medicine, Canada.
Meagan D McLarenCanadian College of Naturopathic Medicine, Canada.
Anna GarberCanadian College of Naturopathic Medicine, Canada.
Daniella RemyCanadian College of Naturopathic Medicine, Canada.
Joy BakerCanadian College of Naturopathic Medicine, Canada.
Adam GrattonCanadian College of Naturopathic Medicine, Canada.
Mohammed Ali KalaCanadian College of Naturopathic Medicine, Canada.
Sasha MonteiroCanadian College of Naturopathic Medicine, Canada.
Cara WarderCanadian College of Naturopathic Medicine, Canada.
Alessandra PerciballiCanadian College of Naturopathic Medicine, Canada.
Kieran CooleyCanadian College of Naturopathic Medicine, Canada.
Canadian College of Naturopathic Medicine · CAUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is the respiratory illness caused by the novel coronavirus, SARS-CoV-2. Cytokine storm appears to be a factor in COVID-19 mortality.

Indexed as

ARDS, acute respiratory distress syndromeCCL, C–C motif ligand chemokineCOVID-19COVID-19, coronavirus disease 2019CSF, Colony-stimulating factorCytokineCytokine release syndromeCytokine stormEchinaceaGM-CSF, granulocyte-macrophage colony-stimulating factorHerbal medicineIFN, interferonIL, interleukinMCP, monocyte chemoattractant proteinMIP, macrophage inflammatory proteinSARS-CoV-2, severe acute respiratory syndrome coronavirus 2SARS, Severe acute respiratory syndromeTFN, tumor necrosis factor

Identifiers

PMID34341776
PMCPMC8320399
OpenAlexW3187286621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.