Evidence map›Paper›PMID 34341740›Full record

ArticleQuantitative imaging in medicine and surgery2021

The effect of hypothyroidism on referential background metabolic activity on

Pei Yang, Qiuping Fan, Huawei Cai, Rong Tian, Minggang Su

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. [Frontiers in medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Reproducibility of [18F]FDG PET/CT liver SUV as reference or normalisation factor.European journal of nuclear medicine and molecular imaging · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pei YangDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China.
Qiuping FanDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China.
Huawei CaiDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China.
Rong TianDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China.
Minggang SuDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBackground uptake activity is used as a reference to assess treatment response by positron emission tomography-computed tomography (PET/CT) with 2-deoxy-2-[F-18]fluoro- D-glucose (

methodsWe recruited 36 patients with hypothyroidism and 36 age and gender-matched euthyroid participants. We recorded patient factors and background mean standardized uptake values normalized by lean body mass from the aortic blood pool, liver, and muscle. We compared the patient factors and background standardized uptake values normalized by lean body mass between hypothyroidism patients and the controls. We performed a multivariate analysis to determine the best predictors of the 3 different background standardized uptake values normalized by lean body mass.

resultsPatients with hypothyroidism had higher liver standardized uptake values normalized by lean body mass (1.77±0.33

conclusionsPET/CT scans showed that hypothyroidism patients had increased liver and blood-pool

Indexed as

2-deoxy-2-[F-18]fluoro-D-glucose (18F-FDG)blood poolhypothyroidismliverpositron emission tomography-computed tomography (PET/CT)

Identifiers

PMID34341740
PMCPMC8245933
OpenAlexW3157390600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.