Evidence map›Paper›PMID 34341736›Full record

ArticleQuantitative imaging in medicine and surgery2021

Biphasic GA 68-labeled prostate specific membrane antigen-11 positron emission tomography/computed tomography scans in the differential diagnosis and risk stratification of initial primary prostate cancer.

Lu-Ping Qin, Jie Lv, Ming-Zhao Li, Liang-Jun Xie, Jin-Ping Li, Jian-Fang Li, Mu-Hua Cheng

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Meta-analysis ofCancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu-Ping QinDepartment of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jie LvDepartment of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Ming-Zhao LiDepartment of Urology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Liang-Jun XieDepartment of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jin-Ping LiDepartment of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jian-Fang LiDepartment of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Mu-Hua ChengDepartment of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to assess the value of biphasic GA 68-labeled prostate-specific membrane antigen-11 (

methodsA total of 51 patients with PCa (8 low- and intermediate-risk PCa patients and 43 high-risk PCa patients) and 36 patients with benign prostate lesions, who underwent standard whole-body imaging and delayed pelvic imaging of

resultsAll the PET parameters of PCa participants were significantly higher than those of participants with benign prostate lesions (P<0.001). The SUVmean of delayed imaging had the best performance in the diagnosis of PCa with an area under the curve (AUC) of 0.918 (95% CI: 0.858 to 0.977), the sensitivity of 90.0%, and specificity of 83.3%. The SUVmax and SUVmean of high-risk PCa participants were significantly higher than those of low- and intermediate-risk PCa participants (P<0.005). The SUVmax of standard imaging had the best performance in predicting high-risk PCa with an AUC of 0.890 (95% CI: 0.799 to 0.980), a sensitivity of 76.7%, and a specificity of 100.0%.

conclusionsThe biphasic

Indexed as

68Ga-PSMA-11differential diagnosisdiphaseInitial prostate cancerrisk stratification

Identifiers

PMID34341736
PMCPMC8245961

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.