ArticleQuantitative imaging in medicine and surgery2021
Investigating the association between ground-glass nodules glucose metabolism and the invasive growth pattern of early lung adenocarcinoma.
Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Diagnostic accuracy of low-dose dual-input computed tomography perfusion in the differential diagnosis of pulmonary benign and malignant ground-glass nodules.Scientific reports · 2024Article
- Establishing and validation of the VBV score for assessing Lung ground-glass nodules based on high-resolution computed tomography.Journal of cardiothoracic surgery · 2024Article
- The value of preoperative positron emission tomography/computed tomography in differentiating the invasive degree of hypometabolic lung adenocarcinoma.BMC medical imaging · 2023Article
- An integrated nomogram combined semantic-radiomic features to predict invasive pulmonary adenocarcinomas in subjects with persistent subsolid nodules.Quantitative imaging in medicine and surgery · 2023Article
- A nomogram based onQuantitative imaging in medicine and surgery · 2022Article
- Diagnosis of diffuse parenchymal lung diseases using transbronchial cryobiopsy guided by endobronchial ultrasound compared to clinicoradiological diagnosis.Quantitative imaging in medicine and surgery · 2022Article
- Adding predictive and diagnostic values of pulmonary ground-glass nodules on lung cancerFrontiers in medicine · 2022Review
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo explore the association between the glucose metabolism level of lung ground-glass nodules (GGNs), as revealed by
methodsWe retrospectively analyzed patients who underwent PET/CT examination and surgical resection due to persistent GGNs, which were confirmed to be early lung adenocarcinoma by postoperative pathology examination. After adjusting for confounding factors and performing stratified analysis, we explored the association between the maximum standard uptake value of PET (SUVmax) and the invasive pathological growth pattern of early stage lung adenocarcinoma.
resultsThe proportions of invasive adenocarcinoma (INV) in the SUVmax of Tertile 1, Tertile 2, and Tertile 3 were 52.7%, 73.3%, and 87.1%, respectively. After adjusting for potential confounding factors, the risk of INV gradually increased as the GGN SUVmax increased [odds ratio (OR): 1.520, 95% confidence interval (CI): 1.044-2.213, P=0.029]. This trend was statistically significant (OR: 1.678, 95% CI: 1.064-2.647, P=0.026), especially in Tertile 3
conclusionsIn FDG PET, the glucose metabolism level (SUVmax) of lung GGNs is independently associated with INV risk, and this association is linear and positive.
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