Evidence map›Paper›PMID 34341724›Full record

ArticleQuantitative imaging in medicine and surgery2021

Recurrence and disease-free survival outcomes after computed tomography-guided needle biopsy in stage IA non-small cell lung cancer patients in China: a propensity score matching analysis.

Chuang He, Hualong Yu, Changyi Li, Xin Zhang, Zhicheng Huang, Mingyang Liu, Lunbing Tong, Jun Zhu, Wei Wu, Xuequan Huang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Chuang HeTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Hualong YuDepartment of Radiology, Affiliated Hospital of Qingdao University, Qingdao, China.
Changyi LiDepartment of Respiratory, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xin ZhangDepartment of Thoracic Surgery, General Hospital of Heilongjiang Province Land Reclamation Bureau, Harbin, China.
Zhicheng HuangDepartment of Radiology, Jilin Provincial Cancer Hospital, Changchun, China.
Mingyang LiuDepartment of Oncology, General Hospital of Heilongjiang Province Land Reclamation Bureau, Harbin, China.
Lunbing TongDepartment of Radiology, Sichuan Police Force Hospital, Leshan, China.
Jun ZhuDepartment of Radiology, The Second People's Hospital of Yibin, Yibin, China.
Wei WuDepartment of Thoracic Surgery, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Xuequan HuangTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Army Medical University · CNHeilongjiang Academy of Land Reclamation Sciences · CNChongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CNJilin Province Tumor Hospital · CNQingdao University · CNSecond People’s Hospital of Yibin · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether preoperative biopsy before radical resection can lead to recurrence and impact patient survival in non-small cell lung cancer (NSCLC) remains controversial. In this study, we carried out a retrospective analysis to determine whether preoperative biopsy can cause disease recurrence and influence disease-free survival (DFS) in patients with stage IA NSCLC.

methodsPatients diagnosed with stage IA NSCLC (solid nodule) between January 2010 and December 2014 were identified from the databases of 7 Chinese medical centers and divided into two groups: a preoperative computed tomography (CT)-guided needle biopsy (CTNB) plus radical resection group, and a non-CTNB group. The propensity score matching (PSM) method was adopted to balance the observed covariates, and Kaplan-Meier estimates were used for survival analysis. Cox regression was used in a single-factor analysis to identify the factors affecting DFS in stage IA NSCLC.

resultsAfter initial screening, 730 patients were enrolled in this study, with 186 and 544 patients in the CTNB group and the non-CTNB group, respectively. After PSM, 186 patients were eventually included in each group. No significant differences in basic clinical features were identified between the two groups (P>0.05). The rates of recurrence were 17.2% and 14.0% in the CTNB and non-CTNB groups (χ

conclusionsCTNB does not increase the incidence of recurrence in stage IA NSCLC or affect patient survival; therefore, it is not a risk factor for DFS. Lung adenocarcinoma and lesion size are risk factors for DFS.

Indexed as

Computed tomography-guided needle biopsy (CTNB)disease-free survival (DFS)stage IA non-small cell lung cancer (stage IA NSCLC)

Identifiers

PMID34341724
PMCPMC8245953
OpenAlexW3158648740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.