Evidence map›Paper›PMID 34341723›Full record

ArticleQuantitative imaging in medicine and surgery2021

Quantitative analysis of repaired rabbit supraspinatus tendons (± channeling) using magnetic resonance imaging at 7 Tesla.

Guy Trudel, Samuel Duchesne-Bélanger, Justin Thomas, Gerd Melkus, Greg O Cron, Peder E Z Larson, Mark Schweitzer, Adnan Sheikh, Hakim Louati, Odette Laneuville

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Guy TrudelBone and Joint Research Laboratory, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Samuel Duchesne-BélangerBone and Joint Research Laboratory, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Justin ThomasBone and Joint Research Laboratory, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Gerd MelkusDepartment of Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada.
Greg O CronDepartment of Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada.
Peder E Z LarsonDepartment of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA.
Mark SchweitzerDepartment of Radiology, Stony Brook University NY, New York, NY, USA.
Adnan SheikhDepartment of Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada.
Hakim LouatiBone and Joint Research Laboratory, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Odette LaneuvilleBone and Joint Research Laboratory, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Ottawa Hospital · CAUniversity of Ottawa · CAOttawa Hospital Research InstituteStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe quantitative assessment of supraspinatus tendons by conventional magnetic resonance is limited by low contrast-to-noise ratio (CNR). Magnetic resonance imaging (MRI) scanners operating at 7 Tesla offer high signal-to noise ratio (SNR), low CNR and high spatial resolution that are well-suited for rapidly relaxing tissues like tendons. Few studies have applied T2 and T2* mapping to musculoskeletal imaging and to the rotator cuff tendons. Our objective was to analyze the T2 and T2* relaxation times from surgically repaired supraspinatus tendons and the effect of bone channeling.

methodsOne supraspinatus tendon of 112 adult female New Zealand white rabbits was surgically detached and repaired one week later. Rabbits were randomly assigned to channeling (n=64) or control (n=48) groups and harvested at 0, 1, 2, and 4 weeks. A 7T magnet was used for signal acquisition. For T2 mapping, a sagittal multi slice 2D multi-echo spin-echo (MESE) CPMG sequence with fat saturation was applied and T2* mapping was performed using a 3D UTE sequence. Magnetic resonance images from supraspinatus tendons were analyzed by two raters. Three regions of interest were manually drawn on the first T2-weighted dataset. For T2 and T2*, different ROI masks were generated to obtain relaxation times.

resultsT2-weighted maps but not T2*-weighted maps generated reliable signals for relaxation time measurement. Torn supraspinatus tendons had lower T2 than controls at the time of repair (20.0±3.4

conclusionsSupraspinatus tendons detached for 1 week had shorter T2 relaxation time compared to contralateral as measured with 7T MRI.

Indexed as

7 Teslasurgical re-attachmentT2 relaxation timestendon

Identifiers

PMID34341723
PMCPMC8245966
OpenAlexW3165329367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.