Evidence map›Paper›PMID 34341439›Full record

ArticleScientific reports2021

Metabolomics-based discrimination of patients with remitted depression from healthy controls using

Ching-I Hung, Gigin Lin, Meng-Han Chiang, Chih-Yung Chiu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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  6. Computational and structural biotechnology journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ching-I HungDepartment of Psychiatry, Chang-Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.
Gigin LinCollege of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.
Meng-Han ChiangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.
Chih-Yung ChiuCollege of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC. pedchestic@gmail.com.
Chang Gung Memorial Hospital · TWChang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to investigate differences in metabolic profiles between patients with major depressive disorder (MDD) with full remission (FR) and healthy controls (HCs). A total of 119 age-matched MDD patients with FR (n = 47) and HCs (n = 72) were enrolled and randomly split into training and testing sets. A

Indexed as

BiomarkersMajor Depressive DisorderMetabolomicsAdultCase-Control StudiesFemaleHumansMaleMetabolomeMiddle AgedProton Magnetic Resonance SpectroscopySupport Vector MachineBiomarkers

Identifiers

PMID34341439
PMCPMC8329159
OpenAlexW3187731484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.