ArticleScientific reports2021
Mueller matrix imaging for collagen scoring in mice model of pregnancy.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Cost-effective Mueller matrix microscopy for label-free differentiation of melanoma from normal skin and common skin cancer types.Biomedical optics express · 2025Article
- Retardance and depolarization of brain white matter as markers for intraoperative delineation of brain tumors: experiments and simulations.Biomedical optics express · 2025Article
- Multi-parametric quantitative evaluation of murine cervical remodeling during pregnancy and postpartum.Scientific reports · 2025Article
- Quantitative Assessment of Collagen Remodeling during a Murine Pregnancy.ACS photonics · 2024Article
- Time-efficient filtering of imaging polarimetric data by checking physical realizability of experimental mueller matrices.Bioinformatics (Oxford, England) · 2024Article
- Speculum-free portable preterm imaging system.Journal of biomedical optics · 2024Article
- Impact of corpus callosum fiber tract crossing on polarimetric images of human brain histological sections:Journal of biomedical optics · 2023Article
- Robustness of the wide-field imaging Mueller polarimetry for brain tissue differentiation and white matter fiber tract identification in a surgery-like environment: anBiomedical optics express · 2023Article
- Spatial frequency domain Mueller matrix imaging.Journal of biomedical optics · 2022Article
- Birefringence effect studies of collagen formed by nonenzymatic glycation using dual-retarder Mueller polarimetry.Journal of biomedical optics · 2022Article
- Combined Mueller matrix imaging and artificial intelligence classification framework for Hepatitis B detection.Journal of biomedical optics · 2022Article
- Toward the development of a polarimetric tool to diagnose the fibrotic human ventricular myocardium.Journal of biomedical optics · 2022Article
- Article
- Polarimetric visualization of healthy brain fiber tracts under adverse conditions:Biomedical optics express · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Preterm birth risk is associated with early softening of the uterine cervix in pregnancy due to the accelerated remodeling of collagen extracellular matrix. Studies of mice model of pregnancy were performed with an imaging Mueller polarimeter at different time points of pregnancy to find polarimetric parameters for collagen scoring. Mueller matrix images of the unstained sections of mice uterine cervices were taken at day 6 and day 18 of 19-days gestation period and at different spatial locations through the cervices. The logarithmic decomposition of the recorded Mueller matrices mapped the depolarization, linear retardance, and azimuth of the optical axis of cervical tissue. These images highlighted both the inner structure of cervix and the arrangement of cervical collagen fibers confirmed by the second harmonic generation microscopy. The statistical analysis and two-Gaussians fit of the distributions of linear retardance and linear depolarization in the entire images of cervical tissue (without manual selection of the specific regions of interest) quantified the randomization of collagen fibers alignment with gestation time. At day 18 the remodeling of cervical extracellular matrix of collagen was measurable at the external cervical os that is available for the direct optical observations in vivo. It supports the assumption that imaging Mueller polarimetry holds promise for the fast and accurate collagen scoring in pregnancy and the assessment of the preterm birth risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.