Evidence map›Paper›PMID 34341387›Full record

ArticleScientific reports2021

Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study.

Mette Pernille Myklebust, Anna Thor, Benedikte Rosenlund, Peder Gjengstø, Ása Karlsdottir, Marianne Brydøy, Bogdan S Bercea, Christian Olsen, Ida Johnson, Mathilde I Berg and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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  11. Detection of Recurrence through microRNA-371a-3p Serum Levels in a Follow-up of Stage I Testicular Germ Cell Tumors in the DRKS-00019223 Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Mette Pernille MyklebustMohn Cancer Research Laboratory, Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91B, 5021, Bergen, Norway. mette.pernille.myklebust@helse-bergen.no.ORCID 0000-0002-3552-3747
Anna ThorDepartment of Urology and CLINTEC Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Benedikte RosenlundMohn Cancer Research Laboratory, Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91B, 5021, Bergen, Norway.
Peder GjengstøDepartment of Urology, Haukeland University Hospital, Bergen, Norway.
Ása KarlsdottirMohn Cancer Research Laboratory, Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91B, 5021, Bergen, Norway.
Marianne BrydøyMohn Cancer Research Laboratory, Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91B, 5021, Bergen, Norway.
Bogdan S BerceaDepartment of Urology, Helse Fonna, Haugesund, Norway.
Christian OlsenMohn Cancer Research Laboratory, Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91B, 5021, Bergen, Norway.
Ida JohnsonDepartment of Urology, Oslo University Hospital, Oslo, Norway.
Mathilde I BergDepartment of Urology, Oslo University Hospital, Oslo, Norway.
Carl W LangbergThe Cancer Centre, Oslo University Hospital, Oslo, Norway.
Kristine E AndreassenThe Cancer Centre, Oslo University Hospital, Oslo, Norway.
Anders KjellmanDepartment of Urology and CLINTEC Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Hege S HaugnesDepartment of Oncology, University Hospital of North Norway, Tromsø, Norway.
Olav DahlMohn Cancer Research Laboratory, Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91B, 5021, Bergen, Norway.
Haukeland University Hospital · NOOslo University Hospital · NOKarolinska University Hospital · SEFonna Hospital TrustUniversity Hospital of North Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA-371a-3p (miR371) has been suggested as a sensitive biomarker in testicular germ cell cancer (TGCC). We aimed to compare miR371 with the classical biomarkers α-fetoprotein (AFP) and β-human chorionic gonadotropin (hCG

Indexed as

OrchiectomyPolymerase Chain ReactionAdolescentAdultalpha-FetoproteinsBiomarkers, TumorChorionic GonadotropinGene Expression Regulation, NeoplasticHumansMicroRNAsMiddle AgedNeoplasms, Germ Cell and EmbryonalNeoplasm StagingProspective StudiesReproducibility of ResultsRNA Stabilityalpha-FetoproteinsBiomarkers, TumorChorionic GonadotropinMicroRNAsMIRN371 microRNA, human

Identifiers

PMID34341387
PMCPMC8329070
OpenAlexW3191813620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.