Evidence map›Paper›PMID 34341193›Full record

ArticleActa crystallographica. Section F, Structural biology communications2021

The X-ray structure of L-threonine dehydrogenase from the common hospital pathogen Clostridium difficile.

Eyram Adjogatse, Josh Bennett, Jingxu Guo, Peter T Erskine, Steve P Wood, Brendan W Wren, Jonathan B Cooper

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Improving enzymatic properties of BlTDH fromFood chemistry. Molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Eyram AdjogatseDivision of Medicine, UCL, Gower Street, London WC1E 6BT, England.
Josh BennettDivision of Medicine, UCL, Gower Street, London WC1E 6BT, England.
Jingxu GuoDivision of Medicine, UCL, Gower Street, London WC1E 6BT, England.
Peter T ErskineDivision of Medicine, UCL, Gower Street, London WC1E 6BT, England.
Steve P WoodDivision of Medicine, UCL, Gower Street, London WC1E 6BT, England.
Brendan W WrenLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.
Jonathan B CooperDivision of Medicine, UCL, Gower Street, London WC1E 6BT, England.
University College London · GBBirkbeck, University of London · GBLondon School of Hygiene & Tropical Medicine · GBUniversity of Portsmouth · GB

Funding

Medical Research Council MR/K000551/1
6 · The paper itself

Abstract

In many prokaryotes, the first step of threonine metabolism is catalysed by the enzyme threonine dehydrogenase (TDH), which uses NAD

Indexed as

Cross InfectionAlcohol OxidoreductasesAmino Acid SequenceClostridioides difficileCrystallography, X-RayHumansProtein Structure, SecondaryProtein Structure, TertiaryX-Ray DiffractionAlcohol OxidoreductasesL-threonine 3-dehydrogenaseClostridium difficilemolecular replacementprotein crystallographyrefinementthreonine dehydrogenase

Identifiers

PMID34341193
PMCPMC8329716
OpenAlexW3170999880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.