Evidence map›Paper›PMID 34341014›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2021

Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey.

Ky'Era V Actkins, Swetha Srinivasan, Lisa P Spees, Erin Turbitt, Caitlin G Allen, Megan C Roberts

Open access · bronzeAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ky'Era V ActkinsDepartment of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, Tennessee.ORCID 0000-0002-1591-6914
Swetha SrinivasanDivision of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-8330-1751
Lisa P SpeesDepartment of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-5680-9330
Erin TurbittDiscipline of Genetic Counselling, Graduate School of Health, University of Technology Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-6650-9702
Caitlin G AllenDepartment of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Megan C RobertsDivision of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. megan.roberts@unc.edu.
University of North Carolina at Chapel Hill · USEmory University · USMeharry Medical College · USUniversity of Technology Sydney · AU

Funding

North Carolina Translational and Clinical Science Institute (NC TraCS) KL2KL2TR002490 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEINBERGER, MORRIS · 2018 to 2022
$11.0M
Improving Family Cancer History Collection using Social Network, Human Centered Design, and Implementation Science ApproachesK00CA253576 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ALLEN, CAITLIN GLOECKNER · 2020 to 2024
$443k
Investigating the genetic and clinical determinants of polycystic ovary syndromeF31HD103397 · NICHD · MEHARRY MEDICAL COLLEGE · PI ACTKINS, KY'ERA · 2021 to 2021
$36k
NCATS NIH HHS KL2 TR002490NCI NIH HHS F99 CA253576NCI NIH HHS K00 CA253576NICHD NIH HHS F31 HD103397
6 · The paper itself

Abstract

Lynch syndrome is the most common inherited cancer syndrome that increases the risk of developing colorectal and endometrial cancer. Universal screening guidelines were first recommended by the Centers for Disease Control and Prevention (CDC) in 2009 and are updated annually by multiple societies. Therefore, one would expect genetic testing rates to increase over time. But testing remains underutilized among those with colorectal or endometrial cancer, even though early detection can improve prognosis and survival rates. In this study, we aimed to understand differences in genetic testing uptake among those with colorectal cancer or endometrial cancer from 2005, 2010, 2015, using data from the National Health Interview Survey (NHIS). We examined genetic testing uptake across cancer-type, age (≤50 or ≥51), sex, race, insurance, and education using a χ

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesColorectal Neoplasms, Hereditary NonpolyposisCross-Sectional StudiesEarly Detection of CancerFemaleGenetic Predisposition to DiseaseGenetic TestingHumansInterviews as TopicMaleMiddle AgedPatient ParticipationRisk Factors

Identifiers

PMID34341014
PMCPMC8492535
OpenAlexW3187654424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.