Evidence map›Paper›PMID 34340552›Full record

ArticlemBio2021

Sulfation of Arabinogalactan Proteins Confers Privileged Nutrient Status to Bacteroides plebeius.

Jose Munoz-Munoz, Didier Ndeh, Pedro Fernandez-Julia, Gemma Walton, Bernard Henrissat, Harry J Gilbert

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Gut colonization ofMicrobiology spectrum · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Jose Munoz-MunozBiosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom.
Didier NdehBiosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom.
Pedro Fernandez-JuliaMicrobial Enzymology Group, Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom.
Gemma WaltonDepartment of Food and Nutritional Sciences, Whiteknights, University of Reading, Reading, United Kingdom.
Bernard HenrissatDTU Bioengineering, Technical University of Denmark, Lyngby, Denmark.
Harry J GilbertBiosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom.
Newcastle University · GBNorthumbria University · GBKing Abdulaziz University · SAUniversity of Reading · GB

Funding

Wellcome TrustWellcome Trust WT097907MA
6 · The paper itself

Abstract

The human gut microbiota (HGM) contributes to the physiology and health of its host. The health benefits provided by dietary manipulation of the HGM require knowledge of how glycans, the major nutrients available to this ecosystem, are metabolized. Arabinogalactan proteins (AGPs) are a ubiquitous feature of plant polysaccharides available to the HGM. Although the galactan backbone and galactooligosaccharide side chains of AGPs are conserved, the decorations of these structures are highly variable. Here, we tested the hypothesis that these variations in arabinogalactan decoration provide a selection mechanism for specific

Indexed as

BacteroidesDietary CarbohydratesGastrointestinal MicrobiomeMucoproteinsNutrientsPlant ProteinsPolysaccharide-LyasesPolysaccharidesSulfatasesarabinogalactan proteinsDietary CarbohydratesMucoproteinsNutrientsPlant ProteinsPolysaccharide-LyasesPolysaccharidesSulfatasesarabinogalactanBacteroidesglycan-degrading enzymeshuman microbiotamicrobial ecologyprivileged nutrientsulfatases

Identifiers

PMID34340552
PMCPMC8406133
OpenAlexW3185636466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.