Evidence map›Paper›PMID 34340542›Full record

ArticlemBio2021

Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice.

Sarah Hulsey Stubbs, Marjorie Cornejo Pontelli, Nischay Mishra, Changhong Zhou, Juliano de Paula Souza, Rosa Maria Mendes Viana, W Ian Lipkin, David M Knipe, Eurico Arruda, Sean P J Whelan

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Sarah Hulsey StubbsDepartment of Microbiology, Harvard Medical Schoolgrid.471403.5, Boston, Massachusetts, USA.
Marjorie Cornejo PontelliDepartment of Molecular Microbiology, Washington University School of Medicine in St. Louis, Saint Louis, Missouri, USA.
Nischay MishraCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
Changhong ZhouDepartment of Microbiology, Harvard Medical Schoolgrid.471403.5, Boston, Massachusetts, USA.
Juliano de Paula SouzaDepartment of Cell and Molecular Biology, Virology Research Center, Ribeirao Preto School of Medicine, University of São Paulo, Ribeirao Preto, São Paulo, Brazil.
Rosa Maria Mendes VianaDepartment of Cell and Molecular Biology, Virology Research Center, Ribeirao Preto School of Medicine, University of São Paulo, Ribeirao Preto, São Paulo, Brazil.
W Ian LipkinCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA.
David M KnipeDepartment of Microbiology, Harvard Medical Schoolgrid.471403.5, Boston, Massachusetts, USA.
Eurico ArrudaDepartment of Cell and Molecular Biology, Virology Research Center, Ribeirao Preto School of Medicine, University of São Paulo, Ribeirao Preto, São Paulo, Brazil.
Sean P J WhelanDepartment of Molecular Microbiology, Washington University School of Medicine in St. Louis, Saint Louis, Missouri, USA.
Harvard University · USUniversidade de São Paulo · BRColumbia University · USWashington University in St. Louis · US

Funding

Small-molecule inhibitors of flavivirus entryU19AI109740 · NIAID · HARVARD MEDICAL SCHOOL · PI WHELAN, SEAN PJ · 2014 to 2018
$23.0M
VIral and host mechanisms that tilt the HSV lytic/latent balanceP01AI098681 · NIAID · HARVARD MEDICAL SCHOOL · PI PESOLA, JEAN M · 2013 to 2023
$19.2M
International Herpes Vaccine ProjectR01AI057552 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KNIPE, DAVID M. · 2005 to 2014
$3.8M
International Herpes Vaccine ProjectR56AI057552 · NIAID · HARVARD MEDICAL SCHOOL · PI KNIPE, DAVID M. · 2011 to 2011
$70k
NIAID NIH HHS P01 AI098681NIAID NIH HHS R01 AI057552NIAID NIH HHS R56 AI057552NIAID NIH HHS U19 AI109740
6 · The paper itself

Abstract

Oropouche virus (OROV) infection of humans is associated with a debilitating febrile illness that can progress to meningitis or encephalitis. First isolated from a forest worker in Trinidad and Tobago in 1955, the arbovirus OROV has since been detected throughout the Amazon basin with an estimated 500,000 human infections over 60 years. Like other members of the family

Indexed as

Genome, ViralAnimalsAntibodies, NeutralizingBunyaviridae InfectionsMaleMiceMice, Inbred C57BLOrthobunyavirusVesicular StomatitisVesiculovirusViral Envelope ProteinsVirus ReplicationAntibodies, NeutralizingViral Envelope Proteinsarbovirusbunyavirusemerging infectious diseasesOropouche virusvaccines

Identifiers

PMID34340542
PMCPMC8406270
OpenAlexW3191103497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.