ArticleACS applied materials & interfaces2021
TiO
Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 96 citations in OpenAlex.
- Polymer-Based Hydrogels for Chemical Biosensing: From Bioreceptor Integration to Smart Applications.ACS applied polymer materials · 2026Review
- Green Approaches Based on Biodegradable Polymers for Sustainable Electrochemical Sensors.Sensors (Basel, Switzerland) · 2026Review
- Tailoring Alginate Hydrogels via Precoordinated Lanthanide Complexes as Dynamic Cross-Linkers.Biomacromolecules · 2026Article
- Swab-based colorimetric determination of tear lactate using lactate oxidase-copper hybrid nanoflowers.Mikrochimica acta · 2026Article
- Flexible polymeric materials and wearable biosensors for smart diabetes mellitus diagnostics and monitoring.iScience · 2026Review
- Lighting the Path to Precision Healthcare: Advances and Applications of Wearable Photonic Sensors.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Engineered Nanofiber-Hydrogel Systems for Colorimetric Lactate Sensing from Breath.ACS applied materials & interfaces · 2025Article
- Revolutionizing healthcare with nanosensor technology.RSC advances · 2025Review
- Ultrasound- and NIR-Responsive Polydextran/Black TiOACS applied materials & interfaces · 2025Article
- Review
- Peroxidase (POD) Mimicking Activity of Different Types of Poly(ethyleneimine)-Mediated Prussian Blue Nanoparticles.Nanomaterials (Basel, Switzerland) · 2024Article
- A new colorimetric lactate biosensor based on CUPRAC reagent using binary enzyme (lactate-pyruvate oxidases)-immobilized silanized magnetite nanoparticles.Mikrochimica acta · 2024Article
- Review
- Simultaneous detection of urea and lactate in sweat based on a wearable sweat biosensor.Biomedical optics express · 2024Article
- Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications.Beilstein journal of nanotechnology · 2024Review
- Enrichment of sweat-derived extracellular vesicles of human and bacterial origin for biomarker identification.Nanotheranostics · 2024Article
- Advances in Non-Electrochemical Sensing of Human Sweat Biomarkers: From Sweat Sampling to Signal Reading.Biosensors · 2023Review
- Advanced Nanostructured Coatings Based on Doped TiOMolecules (Basel, Switzerland) · 2023Review
- Photoactive hydrogels for pre-concentration, labelling, and controlled release of proteins.The Analyst · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Versatile sensing matrixes are essential for the development of enzyme-immobilized optical biosensors. A novel three-dimensional titanium dioxide nanotubes/alginate hydrogel scaffold is proposed for the detection of sweat biomarkers, lactate, and glucose in artificial sweat. Hydrothermally synthesized titanium dioxide nanotubes were introduced to the alginate polymeric matrix, followed by cross-linking nanocomposite with dicationic calcium ions to fabricate the scaffold platform. Rapid colorimetric detection (blue color optical signal) was carried out for both lactate and glucose biomarkers in artificial sweat at 4 and 6 min, respectively. The superhydrophilicity and the capillarity of the synthesized titanium dioxide nanotubes, when incorporated into the alginate matrix, facilitate the rapid transfer of the artificial sweat components throughout the sensor scaffold, decreasing the detection times. Moreover, the scaffold was integrated on a cellulose paper to demonstrate the adaptability of the material to other matrixes, obtaining fast and homogeneous colorimetric detection of lactate and glucose in the paper substrate when image analysis was performed. The properties of this new composite provide new avenues in the development of paper-based sensor devices. The biocompatibility, the efficient immobilization of biological enzymes/colorimetric assays, and the quick optical signal readout behavior of the titanium dioxide nanotubes/alginate hydrogel scaffolds provide a prospective opportunity for integration into wearable devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.