Evidence map›Paper›PMID 34340161›Full record

ArticleDrug and alcohol dependence2021

Posttraumatic stress symptom clusters differentially predict late positive potential to cocaine imagery cues in trauma-exposed adults with cocaine use disorder.

Heather E Webber, Danielle A Kessler, Emma C Lathan, Margaret C Wardle, Charles E Green, Joy M Schmitz, Scott D Lane, Anka A Vujanovic

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Heather E WebberFaillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, United States. Electronic address: Heather.E.Webber@uth.tmc.edu.
Danielle A KesslerDepartment of Psychology, Rice University, Houston, TX, United States.
Emma C LathanFaillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, United States.
Margaret C WardleDepartment of Psychology, University of Illinois at Chicago, Chicago, IL, United States.
Charles E GreenDepartment of Pediatrics, McGovern Medical School, University of Texas Health Science, Center at Houston, Houston, TX, United States.
Joy M SchmitzFaillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, United States.
Scott D LaneFaillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, United States.
Anka A VujanovicDepartment of Psychology, University of Houston, Houston, TX, United States.
The University of Texas Health Science Center at Houston · USRice University · USThe University of Texas Health Science Center · USUniversity of Houston · USUniversity of Illinois Chicago · US

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
Developing Adaptive Interventions for Cocaine Cessation and Relapse PreventionR01DA039125 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SCHMITZ, JOY MARIE · 2016 to 2019
$1.9M
Using event-related potentials to predict treatment outcomes in cocaine use disorderF32DA048542 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WEBBER, HEATHER E · 2020 to 2021
$134k
NCATS NIH HHS UL1 TR003167NIDA NIH HHS F32 DA048542NIDA NIH HHS R01 DA039125
6 · The paper itself

Abstract

backgroundWhile studies have investigated the effects of posttraumatic stress disorder (PTSD) symptoms on substance use, information on these associations in the context of drug cue reactivity is lacking, which can provide meaningful information about risk for relapse. The current study assessed the associations between PTSD symptom clusters and reactivity to cues in trauma-exposed adults with cocaine use disorder.

methodsWe recorded electroencephalogram on 52 trauma-exposed participants (M

resultsLinear mixed modeling indicated that higher NACM symptomatology was associated with higher LPPs to cocaine cues and higher arousal/reactivity was associated with lower LPPs to cocaine cues.

conclusionsThese results highlight the potential clinical utility of the LPP in assessing drug cue reactivity in trauma-exposed adults with substance use disorder.

Indexed as

CocaineStress Disorders, Post-TraumaticSubstance-Related DisordersAdultCuesFemaleHumansMaleMiddle AgedSyndromeCocaineCocaine use disorderCue reactivityLate positive potentialMoodPTSDTrauma

Identifiers

PMID34340161
PMCPMC8464512
OpenAlexW3185146977

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.