Evidence map›Paper›PMID 34339862›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam.

Nguyen Van Vinh Chau, Le Nguyen Thanh Nhan, Lam Anh Nguyet, Nguyen Thi Kha Tu, Nguyen Thi Thu Hong, Dinh Nguyen Huy Man, Dinh Thi Bich Ty, Le Nguyen Truc Nhu, Lam Minh Yen, Truong Huu Khanh and 11 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Nguyen Van Vinh ChauHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Le Nguyen Thanh NhanChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Lam Anh NguyetOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Nguyen Thi Kha TuDong Thap Provincial Center for Disease Control, Dong Thap Province, Vietnam.
Nguyen Thi Thu HongOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Dinh Nguyen Huy ManHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Dinh Thi Bich TyHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Le Nguyen Truc NhuOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Lam Minh YenOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Truong Huu KhanhChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Du Tuan QuyChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Ngo Ngoc Quang MinhChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Nguyen Thi Han NyOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Danielle AndersonDuke-NUS Medical School, Singapore.
Lin-Fa WangDuke-NUS Medical School, Singapore; SingHealth Duke-NUS Global Health Institute, Singapore.
H Rogier van DoornOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Nguyen Thanh HungChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Tran Tan ThanhOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Guy ThwaitesOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Le Van TanOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam. Electronic address: tanlv@oucru.org.
for OUCRU COVID-19 research group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We tested pre-pandemic (2015--2019) plasma samples from 148 Vietnamese children and 100 Vietnamese adults at high risk of zoonotic infections for antibodies against SARS-CoV-2 nucleocapsid and spike proteins. None was positive. The data thus demonstrated no evidence of prior serological cross-reactivity with SARS-CoV-2 that might explain the low numbers of COVID-19 in Vietnam. No pre-existing cross-reactivity might explain Vietnam success of COVID-19 control.

Indexed as

COVID-19SARS-CoV-2AdultAntibodies, ViralChildHumansPandemicsVietnamAntibodies, ViralCOVID-19Cross-reactivitySARS-CoV-2zoonosis

Identifiers

PMID34339862
PMCPMC8324399

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.