ArticleEnvironmental research2022
Urinary glyphosate concentration in pregnant women in relation to length of gestation.
Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 67 citations in OpenAlex.
- Urinary Glyphosate Concentrations among Pregnant Participants in a Randomized, Crossover Trial of Organic and Conventional Diets.Environmental health perspectives · 2023Trial
- Associations of glyphosate exposure in pregnancy with preterm birth: a longitudinal birth cohort study.Environmental pollution (Barking, Essex : 1987) · 2026Article
- Selective Fluorescence Detection of Glyphosate Pesticide Residue Based on FeSensors (Basel, Switzerland) · 2026Article
- Article
- Associations of glyphosate and aminomethylphosphonic acid (AMPA) concentrations with birth outcomes in pregnant women from the Midwestern U.S.International journal of hygiene and environmental health · 2026Article
- Global Evidence on Monitoring Human Pesticide Exposure.Journal of xenobiotics · 2025Review
- First trimester urine glyphosate concentrations and gestational diabetes in nulliparas: a nested case-control study.Environmental health : a global access science source · 2025Article
- Gestational urinary concentrations of glyphosate and aminomethylphosphonic acid in relation to preterm birth: the MIREC study.Journal of exposure science & environmental epidemiology · 2025Article
- Measured exposures to glyphosate in applicators and the general population: an updated review of the scientific literature since 2020.Pest management science · 2025Review
- Exposure to polyoxyethylene tallow amines (POEAs), glyphosate co-formulation surfactants, in a US pregnant population and their potential endocrine disrupting effects.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina.Frontiers in toxicology · 2025Article
- Sociodemographic and dietary determinants of glyphosate exposure in a NYC-based pregnancy cohort.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Relationship of urinary glyphosate concentrations with glycosylated hemoglobin and diabetes in US adults: a cross-sectional study.BMC public health · 2024Article
- Glyphosate and a glyphosate-based herbicide dysregulate the epigenetic landscape of Homeobox A10 (Frontiers in toxicology · 2024Article
- The Effect of Pesticide Spray Season and Residential Proximity to Agriculture on Glyphosate Exposure among Pregnant People in Southern Idaho, 2021.Environmental health perspectives · 2023Article
- Perinatal health effects of herbicides exposures in the United States: the Heartland Study, a Midwestern birth cohort study.BMC public health · 2023Article
- A simple reliable quantification of glyphosate in human urine using MonoSpin TiO extraction and isotope dilution mass spectrometry.Journal of pesticide science · 2023Article
- Maternal pre-conceptional glyphosate exposure impacts the offspring hepatic and ovarian proteome.Toxicological sciences : an official journal of the Society of Toxicology · 2023Article
- Glyphosate exposure and preterm birth: A nested case-control pilot study.Reproductive toxicology (Elmsford, N.Y.) · 2023Article
- Exposures to pesticides and risk of cancer: Evaluation of recent epidemiological evidence in humans and paths forward.International journal of cancer · 2023Article
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Authors and funding
11 authors at 7 institutions in 2 countries.
Funding
Abstract
Human exposure to glyphosate-based herbicides (GBH) is increasing rapidly worldwide. Most existing studies on health effects of glyphosate have focused on occupational settings and cancer outcomes and few have examined this common exposure in relation to the health of pregnant women and newborns in the general population. We investigated associations between prenatal glyphosate exposure and length of gestation in The Infant Development and the Environment Study (TIDES), a multi-center US pregnancy cohort. Glyphosate and its primary degradation product [aminomethylphosphonic acid (AMPA)] were measured in urine samples collected during the second trimester from 163 pregnant women: 69 preterm births (<37 weeks) and 94 term births, the latter randomly selected as a subset of TIDES term births. We examined the relationship between exposure and length of gestation using multivariable logistic regression models (dichotomous outcome; term versus preterm) and with weighted time-to-event Cox proportional hazards models (gestational age in days). We conducted these analyses in the overall sample and secondarily, restricted to women with spontaneous deliveries (n = 90). Glyphosate and AMPA were detected in most urine samples (>94 %). A shortened gestational length was associated with maternal glyphosate (hazard ratio (HR): 1.31, 95 % confidence interval (CI) 1.00-1.71) and AMPA (HR: 1.32, 95%CI: 1.00-1.73) only among spontaneous deliveries using adjusted Cox proportional hazards models. In binary analysis, glyphosate and AMPA were not associated with preterm birth risk (<37 weeks). Our results indicate widespread exposure to glyphosate in the general population which may impact reproductive health by shortening length of gestation. Given the increasing exposure to GBHs and the public health burden of preterm delivery, larger confirmatory studies are needed, especially in vulnerable populations such as pregnant women and newborns.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.