ArticleAngewandte Chemie (International ed. in English)2021
Selective Electrosynthetic Hydrocarboxylation of α,β-Unsaturated Esters with Carbon Dioxide*.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- High-Pressure Electrosynthesis of Succinic and Adipic Acids From COChemSusChem · 2026Article
- Electrochemistry for Sustainable and Low-Carbon Technologies: Energy Conversion, Carbon Neutrality, and Green Chemical Manufacturing.Chemistry, an Asian journal · 2026Review
- Electrochemical selective hydrocarboxylation of acrylamides with carbon dioxide for precise control of α- and β-carboxylation.Communications chemistry · 2025Article
- Electrochemical deutero-(di)carboxylations for the preparation of deuterium-labeled medicinal building blocks.Nature communications · 2025Article
- Wacker Oxidation of Trisubstituted Alkenes: Pd(II)-Catalyzed Oxidative Ring Expansion of Exocyclic α,β-Unsaturated Carbonyl to 2-Fluoro-1,3-Dicarbonyl Compounds.Angewandte Chemie (International ed. in English) · 2025Article
- Vinylogous Electrochemical Carboxylation of Dienones.ACS electrochemistry · 2025Article
- Proximal and Remote Hydrocarboxylation of Alkenes with Carbon Dioxide Enabled by Nickel-Catalyzed Hydrogen Atom Transfer.Angewandte Chemie (International ed. in English) · 2025Article
- Efficient photoelectrochemical system for electrocarboxylation of 1,4-dibromobenzene with COiScience · 2025Article
- Catalytic transformation of carbon dioxide into seven-membered heterocycles and their domino transformation into bicyclic oxazolidinones.Nature communications · 2025Article
- Efficient COMolecules (Basel, Switzerland) · 2024Article
- Nickel-Catalyzed Hydrocarboxylation of Terminal Unactivated Alkenes: Formation of Branched Carboxylic Acids and Competing Catalyst Deactivation from COOrganometallics · 2024Article
- Visible-light-driven alkene dicarboxylation with formate and COChemical science · 2024Article
- Electrochemical Late-Stage Functionalization.Chemical reviews · 2023Review
- Radical Hydrocarboxylation of Unactivated Alkenes via Photocatalytic Formate Activation.Journal of the American Chemical Society · 2023Article
- Ketone-Olefin Coupling of Aliphatic and Aromatic Carbonyls Catalyzed by Excited-State Acridine Radicals.Journal of the American Chemical Society · 2022Article
- Recent Advances in C(spACS organic & inorganic Au · 2022Review
- Selective Electrosynthetic Hydrocarboxylation of α,β-Unsaturated Esters with Carbon Dioxide*.Angewandte Chemie (International ed. in English) · 2021Article
- Basicity as a Thermodynamic Descriptor of Carbanions Reactivity with Carbon Dioxide: Application to the Carboxylation of α,β-Unsaturated Ketones.Frontiers in chemistry · 2021Article
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Authors and funding
7 authors.
Funding
Abstract
The carboxylation of low-value commodity chemicals to provide higher-value carboxylic acids is of significant interest. Recently alternative routes to the traditional hydroformylation processes that used potentially toxic carbon monoxide and a transition metal catalyst have appeared. A significant challenge has been the selectivity observed for olefin carboxylation. Photochemical methods have shown a viable route towards the hydrocarboxylation of α,β-unsaturated alkenes but rely on the use of an excess reducing or amine reagent. Herein we report our investigations of an electrochemical approach that is able to hydrocarboxylate α,β-unsaturated alkenes with excellent regioselectivity and the ability to carboxylate hindered substrates to afford α-quaternary center carboxylic acids. The reported process requires no chromatography and the products are purified by simple crystallization from the reaction mixture after work-up.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.