ArticlePloS one2021
THz irradiation inhibits cell division by affecting actin dynamics.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Effect of terahertz irradiation on DNA damage repair in living cells.FEBS open bio · 2026Article
- Synergistic terahertz platforms for precision oncology.Theranostics · 2026Review
- 0.46 Terahertz wave irradiation inhibit transcription reaction in liposomes.Scientific reports · 2025Article
- Order-disorder phase transition of cell membrane induced by THz irradiation.Scientific reports · 2025Article
- Effect of terahertz radiation on cells and cellular structures.Frontiers of optoelectronics · 2025Review
- The Transcriptomic Response of Cells of the Thermophilic BacteriumInternational journal of molecular sciences · 2024Article
- The biological effects of terahertz wave radiation-induced injury on neural stem cells.iScience · 2023Article
- Specific Features of the Proteomic Response of Thermophilic BacteriumInternational journal of molecular sciences · 2022Article
- A Comparative Study on the Viability of Normal and Cancerous Cells upon Irradiation with a Steady Beam of THz Rays.Life (Basel, Switzerland) · 2022Article
- Control of actin polymerizationFrontiers in cell and developmental biology · 2022Review
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biological phenomena induced by terahertz (THz) irradiation are described in recent reports, but underlying mechanisms, structural and dynamical change of specific molecules are still unclear. In this paper, we performed time-lapse morphological analysis of human cells and found that THz irradiation halts cell division at cytokinesis. At the end of cytokinesis, the contractile ring, which consists of filamentous actin (F-actin), needs to disappear; however, it remained for 1 hour under THz irradiation. Induction of the functional structures of F-actin was also observed in interphase cells. Similar phenomena were also observed under chemical treatment (jasplakinolide), indicating that THz irradiation assists actin polymerization. We previously reported that THz irradiation enhances the polymerization of purified actin in vitro; our current work shows that it increases cytoplasmic F-actin in vivo. Thus, we identified one of the key biomechanisms affected by THz waves.
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