Evidence map›Paper›PMID 34339298›Full record

ArticleJournal of bacteriology2021

RecA Is Required for the Assembly of RecN into DNA Repair Complexes on the Nucleoid.

Emma K McLean, Justin S Lenhart, Lyle A Simmons

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Purification and In Vitro Analysis of Escherichia coli RecN.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. SMC protein RecN drives RecA filament translocation for in vivo homology search.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emma K McLean *Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Justin S Lenhart *Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Lyle A SimmonsDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-9600-7623
University of Michigan · US

Funding

Novel mechanisms of DNA repair and cell cycle regulation in bacteriaR35GM131772 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lyle Simmons · 2019 to 2026
$2.8M
NIGMS NIH HHS R35 GM131772NIH HHS GM131772
6 · The paper itself

Abstract

Homologous recombination requires the coordinated effort of several proteins to complete break resection, homologous pairing, and resolution of DNA crossover structures. RecN is a conserved bacterial protein important for double-strand break repair and is a member of the structural maintenance of chromosomes (SMC) protein family. Current models in Bacillus subtilis propose that RecN responds to double-stranded breaks prior to RecA and end processing, suggesting that RecN is among the very first proteins responsible for break detection. Here, we investigate the contribution of RecA and end processing by AddAB to RecN recruitment into repair foci

Indexed as

DNA RepairBacillus subtilisBacterial ProteinsDNA, BacterialDNA DamageDNA Restriction EnzymesGene Expression Regulation, BacterialGenotypeRec A RecombinasesBacterial ProteinsDNA, BacterialDNA Restriction EnzymesRec A RecombinasesRecN protein, BacteriaAddABBacillus subtilisdouble-strand break repairend processingRecARecN

Identifiers

PMID34339298
PMCPMC8459773
OpenAlexW3193215976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.