Evidence map›Paper›PMID 34338939›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2022

Anatomical characteristics of the membranous septum are predictive of pacemaker requirement in patients undergoing transcatheter aortic valve replacement.

Jonathan Na, Bryan Nixon, James Childress, Paul Han, Gregory Norcross, Steven Liskov, Jean Jeudy, Alejandro Jimenez Restrepo

Abstract read
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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Late arrhythmic burden in patients with left bundle branch block after TAVR with the Evolut valve.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan NaUniversity of Maryland Medical Center, Baltimore, MD, USA. jonathan.na@som.umaryland.edu.ORCID http://orcid.org/0000-0002-5061-7493
Bryan NixonUniversity of Maryland School of Medicine, Baltimore, MD, USA.
James ChildressUniversity of Maryland Medical Center, Baltimore, MD, USA.
Paul HanUniversity of Maryland Medical Center, Baltimore, MD, USA.
Gregory NorcrossUniversity of Maryland Medical Center, Baltimore, MD, USA.
Steven LiskovUniversity of Maryland Medical Center, Baltimore, MD, USA.
Jean JeudyUniversity of Maryland Medical Center, Baltimore, MD, USA.
Alejandro Jimenez RestrepoUniversity of Maryland Medical Center, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to study the characteristics of the membranous septum (MS) and its relationship with the aortic valve (AoV) and aortic annulus (AA) in patients who required PPM post-TAVR.

methodsWe performed a retrospective case-control study of 144 patients undergoing TAVR from 2016 to 2018. Thirty-four patients, requiring PPM implantation, were compared with 34 matched controls who did not require pacing. The total MS length, supra-annular MS (SA-MS) length, infra-annular MS (IA-MS) length, angle between the plane of the AA and MS (AA-MS), and degree of AoV calcifications (AVC) were obtained from preoperative CT. AoV prosthesis implantation depth was obtained from intra-operative fluoroscopy.

resultsThere were no significant differences in valve type (self-expandable: 23 cases vs 25 controls, and balloon-expandable: 11 vs 9, p = 0.79), degree of AVC (0.65 cm

conclusionThe position of the MS with respect to the AA and MS distance below the annular plane were more closely associated with post-TAVR conduction abnormalities requiring PPM than the absolute length of the MS. Patients undergoing TAVR with such anatomy have a higher risk of requiring PPM and should be monitored for developing these complications.

Indexed as

Aortic Valve StenosisHeart Valve ProsthesisPacemaker, ArtificialTranscatheter Aortic Valve ReplacementAortic ValveCardiac Pacing, ArtificialCase-Control StudiesFluoroscopyHumansRetrospective StudiesRisk FactorsTreatment OutcomeConduction abnormalitiesMembranous septumPermanent pacemaker implantationTranscatheter aortic valve replacement

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.