Evidence map›Paper›PMID 34338883›Full record

Trial reportAmino acids2021

Decreased fasting serum glucogenic amino acids with a higher compared to normal protein diet during energy restriction in women: a randomized controlled trial.

A R Ogilvie, M Watford, G Wu, D Sukumar, J Kwon, S A Shapses

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Amino acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00473031 (Nutritional Regulation of Bone - Aim 1), which is not on this map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00473031 nacompletednot on this map

Nutritional Regulation of Bone - Aim 1

TypeinterventionalSponsorRutgers UniversityRan2007 to 2010Enrolled60ConditionsWeight Loss, Bone DensityArmsCaloric restriction, high protein, Caloric restriction, normal protein, Counseling
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

A R OgilvieDepartment of Nutritional Sciences, Rutgers University and NJ-Institute of Food Health and Nutrition, New Brunswick, NJ, USA.
M WatfordDepartment of Nutritional Sciences, Rutgers University and NJ-Institute of Food Health and Nutrition, New Brunswick, NJ, USA.
G WuDepartment of Animal Science, Texas A&M University, College Station, TX, USA.
D SukumarDepartment of Nutrition Sciences, Drexel University, Philadelphia, PA, USA.
J KwonDepartment of Nutritional Sciences, Rutgers University and NJ-Institute of Food Health and Nutrition, New Brunswick, NJ, USA.
S A ShapsesDepartment of Nutritional Sciences, Rutgers University and NJ-Institute of Food Health and Nutrition, New Brunswick, NJ, USA. shapses@rutgers.edu.ORCID http://orcid.org/0000-0002-3128-2325
Rutgers, The State University of New Jersey · USDrexel University · USTexas A&M University · US

Funding

NUTRITIONAL REGULATION OF BONE TURNOVERR01AG012161 · NIA · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SHAPSES, SUE AMY · 2000 to 2014
$3.4M
NUTRITIONAL REGULATION OF BONE TURNOVERR29AG012161 · NIA · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SHAPSES, SUE AMY · 1994 to 1998
–
National Institute of Food and Agriculture 0153866NIA NIH HHS AG12161
6 · The paper itself

Abstract

Dietary protein alters circulating amino acid (AAs) levels and higher protein intake (HP) is one means of losing weight. We examined 34 overweight and obese women (57 ± 4 years) during 6 months of energy restriction (7.3 ± 3.8% weight loss) divided into groups consuming either normal protein (NP; 18.6 energy% protein) or HP (24.3 energy% protein). There was a reduction in fasting serum glucogenic AAs (p = 0.015) that also associated with greater weight loss (p < 0.05) in the HP group, but not in the NP group. These findings have implications for nutrient prioritization during energy restriction.

Indexed as

DietEnergy IntakeWeight LossAgedAmino AcidsBody CompositionDietary ProteinsFastingFemaleHumansMiddle AgedObesityOverweightAmino AcidsDietary ProteinsDietGlucogenic amino acidsLysineProteinWeight loss

Identifiers

PMID34338883
OpenAlexW3188370999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.