ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2022
Pre-eclampsia is a valuable opportunity to diagnose chronic kidney disease: a multicentre study.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The dilemma of chronic kidney disease and end-stage kidney disease following pre-eclampsia: a literature review and meta-analysis.International urology and nephrology · 2025Pooled it
- A systematic review on the determinants of long-term kidney sequelae after hypertensive diseases of pregnancy.Acta obstetricia et gynecologica Scandinavica · 2025Pooled it
- Chronic kidney disease, female infertility, and medically assisted reproduction: a best practice position statement by the Kidney and Pregnancy Group of the Italian Society of Nephrology.Journal of nephrology · 2023Guideline
- Hypertension Management in Pregnancy and Postpartum.Journal of the American Society of Nephrology : JASN · 2026Review
- The birth of an idea: organizing tailored solutions for uncommon journeys in maternal health.Journal of nephrology · 2025Article
- Recurrence of preeclampsia is common, even during rigorously controlled multidisciplinary follow-up: a pilot experience.Clinical kidney journal · 2025Article
- Pregnancy as a Window to Current and Future Kidney Health-An Opportunity.Kidney international reports · 2025Article
- Association Between Maternal Smoking, Isolated Proteinuria During Pregnancy and Preterm Birth: A Finnish Registry Analysis.Kidney international reports · 2025Article
- Commentary on "The ABCs of post-preeclampsia out-patient nephrology care: the Le Mans strategy": perspective of patients' association (Grossesse Santé contre la pré-éclampsie).Journal of nephrology · 2024Article
- The ABCs of post-preeclampsia outpatient nephrology care: the Le Mans strategy.Journal of nephrology · 2024Article
- Pre-gestational counselling for women living with CKD: starting from the bright side.Clinical kidney journal · 2024Review
- Women should not die of pregnancy-related acute kidney injury (PRAKI): revealing the underwater iceberg of maternal health.Journal of nephrology · 2024Article
- Baseline proteinuria level and adverse outcomes in pregnant women with chronic kidney disease: new evidence and a note of caution.Clinical kidney journal · 2023Article
- Cardiovascular risk management following gestational diabetes and hypertensive disorders of pregnancy: a narrative review.The Medical journal of Australia · 2023Review
- Improving Maternal Health Following Complicated Pregnancy and Glomerulonephritis.Kidney international reports · 2023Article
- Adding creatinine to routine pregnancy tests: a decision tree for calculating the cost of identifying patients with CKD in pregnancy.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Article
- Kidney diseases in women: difference in risks and opportunities.Revista da Associacao Medica Brasileira (1992) · 2023Article
- The Hypertensive Disorders of Pregnancy: A Focus on Definitions for Clinical Nephrologists.Journal of clinical medicine · 2022Review
- Pregnancy and Kidney Diseases: Multidisciplinary Follow-Up and the Vicious Circles Involving Pregnancy and CKD, Preeclampsia, Preterm Delivery and the Kidneys.Journal of clinical medicine · 2022Article
- History of Preeclampsia in Patients Undergoing a Kidney Biopsy: A Biphasic, Multiple-Hit Pathogenic Hypothesis.Kidney international reports · 2022Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-eclampsia (PE) and chronic kidney disease (CKD) are known to be associated. Our objective was to assess the prevalence of CKD in a large multicentre cohort of women without acknowledged CKD who experienced a PE episode.
methodsThe setting for the study was France (Le Mans, Central France) and Italy (Cagliari, Sardinia). The study participants were patients who experienced PE in 2018-19, identified from the obstetric charts. Patients with known-acknowledged CKD were excluded. Only singletons were considered. Persistent (micro)albuminuria was defined as present and confirmed at least 3 months after delivery. CKD was defined according to the Kidney Disease Outcomes Quality Initiative guidelines; urinary alterations or low eGFR confirmed at a distance of at least 3 months, or morphologic changes. Patients were divided into four groups: evidence of CKD; no evidence of CKD; unclear diagnosis-ongoing work-up; or persistent microalbuminuria. The outcome 'diagnosis of CKD' was analysed by simple and multiple logistic regressions. Temporal series (week of delivery) were analysed with Kaplan-Meier curves and Cox analysis.
resultsTwo hundred and eighty-two PE pregnancies were analysed (Le Mans: 162; Cagliari: 120). The incidence of CKD diagnosis was identical (Le Mans: 19.1%; Cagliari: 19.2%); no significant difference was found in unclear-ongoing diagnosis (6.2%; 5.8%) and microalbuminuria (10.5%; 5.8%). Glomerulonephritis and diabetic nephropathy were more frequent in Cagliari (higher age and diabetes prevalence), and interstitial diseases in Le Mans. In the multivariate logistic regression, CKD diagnosis was associated with preterm delivery (adjusted P = 0.035). Gestation was 1 week shorter in patients diagnosed with CKD (Kaplan-Meier P = 0.007). In Cox analysis, CKD remained associated with shorter gestation after adjustment for age and parity.
conclusionsThe prevalence of newly diagnosed CKD is high after PE (19% versus expected 3% in women of childbearing age), supporting a systematic nephrology work-up after PE.
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