Evidence map›Paper›PMID 34338631›Full record

ArticleeLife2021

Uniparental nuclear inheritance following bisexual mating in fungi.

Vikas Yadav, Sheng Sun, Joseph Heitman

Open access · greenAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 citations in OpenAlex.

  1. Meiosis-specific genes play roles in ploidy reduction inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Unisexual reproduction in the global human fungal pathogenProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Meiosis-specific genes play roles in ploidy reduction inbioRxiv : the preprint server for biology · 2025
    Article
  6. Unisexual reproduction in the global human fungal pathogenbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Tracing the evolution and genomic dynamics of mating-type loci inbioRxiv : the preprint server for biology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. On the evolution of variation in sexual reproduction through the prism of eukaryotic microbes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vikas YadavDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.ORCID 0000-0003-2650-9035
Sheng SunDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.ORCID 0000-0002-2895-1153
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, United States.ORCID 0000-0001-6369-5995
Duke University · US

Funding

Structure, function, and evolution of the Cryptococcus MAT locusR01AI050113 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2002 to 2024
$8.5M
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITINGR01AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 1997 to 2025
$6.7M
Genetics of Cryptococcus sexual reproductionR37AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2011 to 2020
$4.9M
NIAID NIH HHS R01 AI039115NIAID NIH HHS R01 AI050113NIAID NIH HHS R37 AI039115
6 · The paper itself

Abstract

Some remarkable animal species require an opposite-sex partner for their sexual development but discard the partner's genome before gamete formation, generating hemi-clonal progeny in a process called hybridogenesis. Here, we discovered a similar phenomenon, termed pseudosexual reproduction, in a basidiomycete human fungal pathogen,

Indexed as

Cell NucleusCryptococcus neoformansFungal ProteinsGenes, Mating Type, FungalHumansMitochondriaReproductionFungal Proteinscryptococcus neoformansCryptococcus neoformansgeneticsgenomicshybridogenesisinfectious diseasemeiosismicrobiologynuclear migrationpseudosexual reproductionsexual parasitism

Identifiers

PMID34338631
PMCPMC8412948
OpenAlexW3110522644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.