Evidence map›Paper›PMID 34338560›Full record

ArticleDrug delivery2021

Facile surface functional polyetheretherketone with antibacterial and immunoregulatory activities for enhanced regeneration toward bacterium-infected bone destruction.

An'an Sun, Xi Lin, Zhiqiang Xue, Jiyue Huang, Xinxin Bai, Lingling Huang, Xinhua Lin, Shaohuang Weng, Min Chen

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

An'an SunDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Xi LinDepartment of Emergency Surgery, Center for Trauma Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Zhiqiang XueDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jiyue HuangDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Xinxin BaiDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Lingling HuangDepartment of Stomatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Xinhua LinDepartment of Pharmaceutical Analysis, School of Pharmacy, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Shaohuang WengDepartment of Pharmaceutical Analysis, School of Pharmacy, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China.
Min ChenDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Existing biologically inert or unmodified implants to treat infectious bone defects or osteomyelitis still cannot effectively solve bacterial infection and osseointegration. In this work, a simple co-deposition strategy was developed to modify porous polyetheretherketone (PEEK) with improved antibacterial activity and controllable immunoregulatory ability. After PEEK was treated by H

Indexed as

Alkaline PhosphataseAnimalsAnti-Bacterial AgentsBenzophenonesBiocompatible MaterialsCell DifferentiationCell LineCell ProliferationDrug ImplantsDrug LiberationEscherichia coliGentamicinsIndolesOsteogenesisPolymersPorosityAlkaline PhosphataseAnti-Bacterial AgentsBenzophenonesBiocompatible MaterialsDrug ImplantsGentamicinsIndolespolydopaminepolyetheretherketonePolymersanti-infectionCo-deposition of polydopamine and gentamicinenhanced osseintegrationimmunoregulatoryPEEK

Identifiers

PMID34338560
PMCPMC8330770
OpenAlexW3192721257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.