Evidence map›Paper›PMID 34337986›Full record

ArticleJournal of managed care & specialty pharmacy2021

Overcoming barriers to biosimilar adoption: real-world perspectives from a national payer and provider initiative.

Babette S Edgar, Adam S Cheifetz, Simon M Helfgott, Gideon P Smith, Tina Bandekar, Adam Hoye-Simek, YuQian Liu, Rubina M Singh, Kristina I Fajardo, Jeffrey Carter and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of managed care & specialty pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Individual Prescribing Incentives for Biosimilars in Selected European Countries and the USA: a Scoping Literature Review.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Article
  7. Article
  8. Demand- Versus Supply-Side Policies in Market Penetration of Biosimilars: Which is More Effective?BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Biosimilars in Dermatology Review.Journal of psoriasis and psoriatic arthritis · 2024
    Review
  18. Review
  19. Factors Associated with Biosimilar Exclusions and Step Therapy Restrictions Among US Commercial Health Plans.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Article
  20. A Framework for Evaluating the Implementation of Biosimilar Drugs.The Canadian journal of hospital pharmacy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Babette S EdgarBluePeak Advisors, Dallas, TX.
Adam S CheifetzBeth Israel Deaconess Medical Center, Boston, MA.
Simon M HelfgottBrigham and Women's Hospital, Boston, MA.
Gideon P SmithMassachusetts General Hospital, Boston, MA.
Tina BandekarBoston Medical Center Health Plan, Boston, MA.
Adam Hoye-SimekDevoted Health, Waltham, MA.
YuQian LiuMagellan Rx Management, Phoenix, AZ.
Rubina M SinghAcademy of Managed Care Pharmacy, Alexandria, VA.
Kristina I FajardoPRIME Education, LLC, Fort Lauderdale, FL.
Jeffrey CarterPRIME Education, LLC, Fort Lauderdale, FL.
Laura SimonePRIME Education, LLC, Fort Lauderdale, FL.
Beth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In response to a published national payer survey indicating striking needs for multistakeholder initiatives to increase biosimilar adoption, a focus workgroup meeting joining payers and providers was conducted in December 2019 in Boston, MA. Before the focus group meeting, a survey was sent to health care providers to collect perceptions about barriers to biosimilar adoption and gather input on best potential strategies for addressing these barriers. The focus group panel consisted of 5 managed care pharmacists and 3 physician experts in rheumatology, dermatology, and gastroenterology, representing large managed care organizations and health care systems in the Boston area. A clinical moderator facilitated discussions between the payers and providers regarding challenges to biosimilar adoption and potential collaborative strategies to overcome these barriers. The focus group participants identified hurdles to biosimilar adoption in 3 major areas: (1) the lack of confidence in biosimilar interchangeability and a need for education about biosimilars, (2) the lack of financial incentives to switch to biosimilars from the reference biologic product, and (3) administrative burdens that impair the prescription of biologics. Learning from their mutual experiences, the focus group participants formulated action plans to address these barriers. The top strategies recommended by the participants included advancing biosimilar education, facilitating administrative processes related to biosimilar prescriptions, and increasing provider reimbursement while reducing cost sharing to patients receiving biosimilars.

Indexed as

Biosimilar PharmaceuticalsDrug SubstitutionFocus GroupsFormularies as TopicHumansPharmaceutical ServicesPractice Patterns, Physicians'Surveys and QuestionnairesBiosimilar Pharmaceuticals

Identifiers

PMID34337986
PMCPMC10391006
OpenAlexW3191544237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.