Evidence map›Paper›PMID 34337580›Full record

ArticleHeart rhythm O22021

Predicting early reconnection after cryoballoon ablation with procedural and biophysical parameters.

Fehmi Keçe, Marta de Riva, Reza Alizadeh Dehnavi, Adrianus P Wijnmaalen, Bart J Mertens, Martin J Schalij, Katja Zeppenfeld, Serge A Trines

Abstract read
In one paragraph

Article in Heart rhythm O2, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Validation of a prediction model for early reconnection after cryoballoon ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  3. Pulsed-field- vs. cryoballoon-based pulmonary vein isolation: lessons from repeat procedures.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  4. Atrial fibrillation cryoablation is an effective day case treatment: the UK PolarX vs. Arctic Front Advance experience.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  5. Cryoballoon temperature parameters during cryoballoon ablation predict pulmonary vein reconnection and atrial fibrillation recurrence.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Fehmi KeçeDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.
Marta de RivaDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.
Reza Alizadeh DehnaviDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.
Adrianus P WijnmaalenDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.
Bart J MertensBioinformatics Center of Expertise, Leiden University Medical Center, Leiden, The Netherlands.
Martin J SchalijDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.
Katja ZeppenfeldDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.
Serge A TrinesDepartment of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPredicting early reconnection/dormant conduction (ERC) immediately after pulmonary vein isolation (PVI) can avoid a waiting period with adenosine testing.

objectiveTo identify procedural and biophysical parameters predicting ERC.

methodsConsecutive atrial fibrillation (AF) patients undergoing a first cryoballoon ablation (Arctic Front Advance) between 2014 and 2017 were included. ERC was defined as manifest or dormant pulmonary vein (PV) reconnection with adenosine 30 minutes after PVI. Time to isolation (TTI), balloon temperatures (BT), and thawing times were evaluated as potential predictors for ERC. Based on a multivariable model, cut-off-values were defined and a formula was constructed to be used in clinical practice.

resultsA total of 136 patients (60 ± 10 years, 96 male, 95% paroxysmal AF) were included. ERC was found in 40 (29%) patients (ERC group) and in 53 of 575 (9%) veins. Procedural and total ablation time and the number of unsuccessful freezes were significantly longer/higher in the ERC group compared to the non-ERC group (150 ± 40 vs 125 ± 34 minutes; 24 ± 5 vs 17 ± 4 minutes, and 38% vs 24%, respectively (

conclusionThree easily available parameters were associated with ERC. Using these parameters during ablation can help to avoid a 30-minute waiting period and adenosine testing.

Indexed as

Atrial fibrillationCryoballoon ablationDormant conductionPulmonary vein isolationTime-to-isolation

Identifiers

PMID34337580
PMCPMC8322820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.