Evidence map›Paper›PMID 34337542›Full record

ArticleEuropean urology open science2021

Addition of Prostate Volume and Prostate-specific Antigen Density to Memorial Sloan Kettering Cancer Center Prostate Cancer Nomograms.

Michael Tzeng, Emily Vertosick, Spyridon P Basourakos, James A Eastham, Behfar Ehdaie, Peter T Scardino, Andrew J Vickers, Jim C Hu

Abstract read
In one paragraph

Article in European urology open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael TzengDepartment of Urology, New York Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA.
Emily VertosickDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Spyridon P BasourakosDepartment of Urology, New York Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA.
James A EasthamUrology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Behfar EhdaieUrology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Peter T ScardinoUrology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Andrew J VickersDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jim C HuDepartment of Urology, New York Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Evaluation of Transperineal Biopsy under Local Anesthesia, a Novel approach to Decrease Post-Biopsy Infections and Improve Cancer DetectionR01CA241758 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALLAF, MOHAMAD, HU, JIM · 2020 to 2024
$3.1M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA241758
6 · The paper itself

Abstract

Prostate-specific antigen (PSA) density is an established prognostic marker for prostate cancer. We investigated whether the inclusion of PSA density or prostate volume in the Memorial Sloan Kettering Cancer Center nomograms improves the prediction of biochemical recurrence (BCR) after radical prostatectomy (RP). Among the 11 725 men included, 2140 developed BCR. Neither PSA density nor prostate volume was associated with BCR when added to either the pre-RP or post-RP model (all PATIENT SUMMARY: Addition of prostate volume or prostate-specific antigen density to Memorial Sloan Kettering Cancer Center prediction schemes did not improve the prediction of recurrence of prostate cancer after removal of the prostate.

Indexed as

Biochemical recurrenceNomogramProstate cancerProstate-specific antigenProstate-specific antigen densityProstate volumeRadical prostatectomy

Identifiers

PMID34337542
PMCPMC8317781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.