Evidence map›Paper›PMID 34337529›Full record

ArticleEuropean urology open science2021

Decreasing Non-bladder-cancer Mortality After Radical Cystectomy.

Michael Froehner, Rainer Koch, Ulrike Heberling, Angelika Borkowetz, Matthias Hübler, Vladimir Novotny, Manfred P Wirth, Christian Thomas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European urology open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michael FroehnerDepartment of Urology, Zeisigwaldkliniken Bethanien Chemnitz, Chemnitz, Germany.
Rainer KochDepartment of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Ulrike HeberlingDepartment of Urology, Zeisigwaldkliniken Bethanien Chemnitz, Chemnitz, Germany.
Angelika BorkowetzDepartment of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Matthias HüblerDepartment of Anesthesiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Vladimir NovotnyDepartment of Urology, Städtisches Klinikum Görlitz, Görlitz, Germany.
Manfred P WirthDepartment of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Christian ThomasDepartment of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
University Hospital Carl Gustav Carus · DEKlinikum Chemnitz · DEKlinikum Görlitz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Life expectancy is increasing in many parts of the world. Using proportional hazard models for competing risks, we investigated whether this increase has changed outcomes after radical cystectomy in a sample of 1419 consecutive patients treated between 1993 and 2018. During the observation period, the mean age and the proportion of patients with American Society of Anesthesiologists physical status class 3 or 4 increased, whereas the proportion of patients with heart disease decreased. Competing mortality (causes other than bladder cancer) decreased in all subgroups (hazard ratios [HRs] per year ranged from 0.931 to 0.963) and after controlling for increasing age (HRs ranged from 1.018 to 1.081). In an optimal model resulting from an analysis including age (HR per year 1.048, 95% confidence interval [CI] 1.027-1.070; PATIENT SUMMARY: In a review of data for 1993-2018, we found that death from other causes after removal of the bladder (radical cystectomy) for bladder cancer decreased over time. This decreasing trend might increase the age limit at which bladder cancer patients can benefit from radical cystectomy in the future.

Indexed as

AgeBladder cancerComorbidityCompeting risk analysisLife expectancyMortalityRadical cystectomySelection

Identifiers

PMID34337529
PMCPMC8317886
OpenAlexW3160834492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.