ArticleEuropean urology open science2021
WATER versus WATER II 2-Year Update: Comparing Aquablation Therapy for Benign Prostatic Hyperplasia in 30-80-cm
Article in European urology open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Complication Profile and Safety Outcomes of Aquablation in the Management of BPH.Medicina (Kaunas, Lithuania) · 2025Pooled it
- One-month postoperative α-blocker therapy reduces morbidity and increases patients' satisfaction and well-being following water jet aquablation for treating benign prostatic obstruction: a randomized prospective trial.Central European journal of urology · 2026Article
- Review
- Increased risk of bleeding during and after HoLEP in patients with prostate cancer: A multicentre comparative cohort study.BJUI compass · 2025Article
- Integrated management strategies for benign prostatic hyperplasia.Frontiers in urology · 2025Review
- Combination Prostatic Artery Embolization Prior to Water-Jet Ablation (Aquablation) for Benign Prostatic Hypertrophy: A Propensity Score Analysis.Journal of clinical medicine · 2024Article
- WATER versus WATER II 5-year update: Comparing Aquablation therapy for benign prostatic hyperplasia in 30-80-cmBJUI compass · 2024Article
- Ablative minimally invasive surgical therapies for benign prostatic hyperplasia: A review of Aquablation, Rezum, and transperineal laser prostate ablation.Prostate cancer and prostatic diseases · 2024Review
- Perioperative Rates of Incidental Prostate Cancer after Aquablation and Holmium Laser Enucleation of the Prostate.Urologia internationalis · 2024Article
- Aquablation Therapy in Large Prostates (80-150 mL) for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: Final WATER II 5-Year Clinical Trial Results.The Journal of urology · 2023Article
- CUA 2022 Annual Meeting Abstracts - Podium Session 1: BPH, GU Trauma and Reconstruction, Neurogenic Bladder, Urinary Incontinence and Voiding Dysfunction, Pediatrics Friday, June 24, 2022 • 13:30-14:30.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Learning curve in aquablation: an international multicenter study.World journal of urology · 2022Article
- Modern advancements in minimally invasive surgical treatments for benign prostatic obstruction.Therapeutic advances in urologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 15 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical options are limited when treating large (>80 cm
objectiveTo compare the outcome of Aquablation for 30-80-cm DESIGN SETTING AND
participantsWe used data from two trials. WATER is a prospective, double-blind, multicenter, international clinical trial comparing the safety and efficacy of Aquablation and transurethral resection of the prostate in the treatment of LUTS/BPH in men aged 45-80 yr with a prostate of 30-80 cm
interventionAquablation, an ultrasound-guided, robotically executed waterjet ablative procedure. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: We compared 24-mo outcomes between 116 WATER and 101 WATER II study subjects. Student's RESULTS AND LIMITATIONS: The International Prostate Symptom Score (IPSS) reductions at 24 mo was 14.5 points for WATER and 17.4 points for WATER II (
conclusionsAquablation is effective in patients with a prostate of 30-80 cm PATIENT SUMMARY: Outcomes of Aquablation for both small-to-moderately-sized and large prostates are similar and sustainable at 2 yr of follow-up.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.