Evidence map›Paper›PMID 34337425›Full record

Article... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics2018

Quantification of Biological Responses as Predictors of Cognitive Outcome after Developmental TBI.

Saman Sargolzaei, Yan Cai, Deborah Lee, Neil G Harris, Christopher C Giza

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saman SargolzaeiDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095.
Yan CaiDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095.
Deborah LeeDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095.
Neil G HarrisDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095.
Christopher C GizaDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095.
University of California, Los Angeles · USMattel Children's Hospital · US

Funding

UCLA Center for Translational Research in Neurodevelopment: UC-TRaNU54HD087101 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2016 to 2020
$6.5M
Using glutamatergic pharmacotherapy to optimize TBI recoveryR01NS027544 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOVDA, DAVID A · 1990 to 2017
$3.8M
A mechanism for stunted map plasticity after TBIR01NS091222 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HARRIS, NEIL · 2015 to 2019
$1.7M
NICHD NIH HHS U54 HD087101NINDS NIH HHS R01 NS027544NINDS NIH HHS R01 NS091222
6 · The paper itself

Abstract

Successful translational studies within the field of Traumatic Brain Injury (TBI) are concerned with determining reliable markers of injury outcome at chronic time points. Determination of injury severity following Fluid Percussion Injury (FPI) has long been limited to the measured atmospheric pressure associated with the delivered pulse. Duration of unresponsiveness to toe pinch (unconsciousness) was next introduced as an extra marker of injury severity. The current study is an effort to assess the utilization of acute injury-induced biological responses (duration of toe pinch unresponsiveness, percent body weight change, quantification of brain edema, and apnea duration) to predict cognitive performance at a subacute time point following developmental brain injury. Cognitive performance, when measured at a subacute phase, after developmental FPI was negatively correlated with the following variables, duration of toe pinch unresponsiveness, percent weight change, and quantified level of brain edema. These finding suggest the potential utilization of reliable severity assessment of injury-induced biological responses in determining outcome measures at subacute time points.

Identifiers

PMID34337425
PMCPMC8320685
OpenAlexW2797948931

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.