Evidence map›Paper›PMID 34337274›Full record

ArticleJournal of the Endocrine Society2021

Calcium-Sensing Receptors Control CYP27B1-Luciferase Expression: Transcriptional and Posttranscriptional Mechanisms.

Alice Huang, Lenah Binmahfouz, Dale P Hancock, Paul H Anderson, Donald T Ward, Arthur D Conigrave

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. The Role of Altered Mineral Metabolism in Kidney Stone Disease: Is Vitamin D the Key?American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Regulation of 1 and 24 hydroxylation of vitamin D metabolites in the proximal tubule.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Alice HuangSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW 2006Australia.
Lenah BinmahfouzFaculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.
Dale P HancockSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW 2006Australia.
Paul H AndersonClinical and Health Sciences, Health and Biomedical Innovation, University of South Australia, Adelaide, SA, 5001, Australia.
Donald T WardFaculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.
Arthur D ConigraveSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW 2006Australia.ORCID https://orcid.org/0000-0002-7232-3891
The University of Sydney · AUKing Abdulaziz University · SAUniversity of Manchester · GBUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

25-hydroxyvitamin D 1α-hydroxylase (encoded by

Indexed as

1αOHasecalcium-sensing receptorCYP27B1ERK1/2PKCprotein breakdownprotein synthesisThr-888 phosphorylationtranscription

Identifiers

PMID34337274
PMCPMC8317635
OpenAlexW3154698562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.