Evidence map›Paper›PMID 34337191›Full record

ArticleExposure and health2021

Low‑Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State.

Shelbie Stahr, Tung-Chin Chiang, Michael A Bauer, Gail A Runnells, Lora J Rogers, Huyen Vi Do, Susan A Kadlubar, L Joseph Su

Open access · hybridAbstract read
In one paragraph

Article in Exposure and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Arsenic, mercury, manganese, and lead exposure in Mexican adults aged 50 and older.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Hair Lead, Aluminum, and Other Toxic Metals in Normal-Weight and Obese Patients with Coronary Heart Disease.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shelbie StahrInterdisciplinary Biomedical Sciences, Department of Clinical and Translational Sciences, University of Arkansas Medical Sciences, 4301 W. Markham St. Slot #601, Little Rock, AR 72205, USA.ORCID 0000-0002-3761-4036
Tung-Chin ChiangDepartment of Environmental and Occupational Health, Fay W. Boozman College of Public Health, University of Arkansas Medical Sciences, 4301 West Markham, # 820, Little Rock, AR 72205, USA.
Michael A BauerDepartment of Biomedical Informatics, College of Medicine, University of Arkansas Medical Sciences, 4018 W Capitol Ave, Little Rock, AR 72205, USA.
Gail A RunnellsDepartment of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas Medical Sciences, 4301 W. Markham St. # 820, Little Rock, AR 72205, USA.
Lora J RogersCOPH Department of Epidemiology Slot 721-21, Winthrop P. Rockefeller Cancer Institute, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4104 Outpatient Circle, Little Rock, AR 72205-7101, USA.
Huyen Vi DoDepartment of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas Medical Sciences, 4301 W. Markham St. # 820, Little Rock, AR 72205, USA.
Susan A KadlubarDepartment of Environmental and Occupational Health, Fay W. Boozman College of Public Health, University of Arkansas Medical Sciences, 4301 West Markham, # 820, Little Rock, AR 72205, USA.
L Joseph SuDepartment of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas Medical Sciences, 4301 W. Markham St. # 820, Little Rock, AR 72205, USA.
University of Arkansas for Medical Sciences · USArkansas Department of Health · USWinthrop Rockefeller Foundation · US

Funding

Arkansas Center for Clinical and Translational ResearchUL1TR000039 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI BECK, CORNELIA MARIE, JAMES, LAURA P · 2012 to 2014
$10.0M
NCATS NIH HHS UL1 TR000039
6 · The paper itself

Abstract

Both arsenic and cadmium are reported to be toxic to humans. The use of saliva as a biomarker of low-level exposures to these elements has not been adequately explored, and the putative relationship between exposure and obesity is unclear. This cross-sectional study aims to investigate the relationship between salivary arsenic and cadmium concentrations and their association with obesity. Arsenic and cadmium concentrations were analyzed in human saliva samples by Inductively Coupled Plasma-Mass Spectrometry on 270 randomly selected women who participated in the Arkansas Rural Community Health Study. Multivariable logistic regression was performed to evaluate the association between heavy metal concentrations and obesity. Stratified logistic regression was performed based on menopausal status. Generalized linear models were used to evaluate weight gain velocity. Significant positive associations were observed in postmenopausal women for both arsenic (OR = 4.43, 95% CI 1.91-10.28) and cadmium (OR = 2.72, 95% CI 1.23-5.99) concentrations, as well as significant trends among tertiles (

Indexed as

ArsenicCadmiumMenopauseObesitySaliva

Identifiers

PMID34337191
PMCPMC8323941
OpenAlexW3124008525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.