Evidence map›Paper›PMID 34337068›Full record

ReviewBioMed research international2021

A View on Polymerase Chain Reaction as an Outstanding Molecular Diagnostic Technique in Periodontology.

Adileh Shirmohammadi, Amirreza Babaloo, Solmaz Maleki Dizaj, Farzaneh Lotfipour, Simin Sharifi, Mohammad Ali Ghavimi, Khadijeh Khezri

Abstract readReview
In one paragraph

Review in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adileh ShirmohammadiDepartment of Periodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-3862-3049
Amirreza BabalooDepartment of Periodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-2535-1232
Solmaz Maleki DizajDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0003-4759-7222
Farzaneh LotfipourFood and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-0284-048X
Simin SharifiDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-3020-3779
Mohammad Ali GhavimiDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-6638-2799
Khadijeh KhezriDeputy of Food and Drug Administration, Urmia University of Medical Sciences, Urmia, Iran.ORCID https://orcid.org/0000-0002-4671-985X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study presents a discussion on the fundamentals of polymerase chain reaction (PCR) and its use as a diagnostic tool in periodontology. MATERIALS AND

methodsA computer-aided as well as hand-made search in PubMed and Scopus indexed journals (relevant to the topic) was done by keywords of molecular technique in periodontology, PCR, applications of PCR, and PCR in periodontics. Only the papers in the English language and outlining PCR and its association with periodontology were collected and utilized to provide a succinct review. There was no limitation for publication time.

resultsThe results of our search showed that PCR has turned into a standard in diagnosis in the field of periodontology. A variety of researches has demonstrated that its sensitive, and specific characteristics make it a quick and effective technique of recognition, identification, and quantification of microorganisms. Identification of various immunoinflammatory markers at the mRNA expression level as well as ascertaining gene-related polymorphisms can also be performed.

conclusionsThe mechanisms of periodontal disease can further become clarified using PCR.

Indexed as

Molecular Diagnostic TechniquesPeriodonticsBiomarkersHumansPeriodontal DiseasesPolymerase Chain ReactionPolymorphism, GeneticBiomarkers

Identifiers

PMID34337068
PMCPMC8315861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.