ArticleBioMed research international2021
Epidemiological Trends of Head and Neck Cancer: A Population-Based Study.
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 54 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognosing post-treatment outcomes of head and neck cancer using structured data and machine learning: A systematic review.PloS one · 2024Pooled it
- Autologous Fat Grafting for Functional and Aesthetic Improvement in Patients with Head and Neck Cancer: A Systematic Review.Aesthetic plastic surgery · 2023Pooled it
- Effectiveness of Oncological Physiotherapy on Shoulder Dysfunction After Cervical Lymph Node Dissection in Head and Neck Cancer: A Pilot Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- The Effect of Expressive Writing on the Experiences of Head and Neck Cancer Patients Undergoing Radiotherapy: A Randomized Controlled Trial.Cancer medicine · 2025Trial
- Rebamipide gargle and benzydamine gargle in prevention and management of chemo-radiotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients (randomized clinical trial).BMC oral health · 2024Trial
- VoiceS: voice quality after transoral COTrials · 2022Trial
- Improved oral health in head and neck cancer survivors (OHHNC study): a study protocol for a multicentre two-armed randomised controlled trial.BMC cancer · 2026Article
- Impact of postoperative radiotherapy on combined local SCC events and survival in non-metastatic oral and pharyngeal squamous cell carcinoma.Discover oncology · 2026Article
- Trajectory patterns and factors associated with shoulder-related quality of life in patients with head and neck cancer after neck dissection: A longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Genetically Predicted Gut Microbiota in Correlation with the Risk of Head and Neck Cancer.Cancer informatics · 2026Article
- BMI and PNI as predictors of treatment completion and survival in locally advanced HNSCC receiving sequential chemoradiotherapy.BMC cancer · 2025Article
- Incidence, Risk Factors, and Epidemiological Trends of Head and Neck Cancer: A Global Analysis.MedComm · 2025Article
- Low Vitamin D and High Psychological Distress: Are They Associated with Poor Differentiation in Head and Neck Cancer?Clinics and practice · 2025Article
- Head and Neck Cancer: Trends and Geographical Distribution of Head and Neck Cancer at a Tertiary Hospital in Northern Tanzania.Laryngoscope investigative otolaryngology · 2025Article
- Time to Onset of Dysphagia Following Head and Neck Radiation.Dysphagia · 2025Article
- The investigation of opening modes of head and neck thermoplastic mask for radiotherapy based on finite element analysis.Radiation oncology (London, England) · 2025Article
- Mortality of Head and Neck Cancer in China From 1990 to 2019: A Secondary Data Analysis.Cancer reports (Hoboken, N.J.) · 2025Article
- Psychometric evaluation of the Chinese version of the Patient Self-Advocacy Scale using classical test theory and item response theory.Scientific reports · 2025Observational
- Global burden, health inequalities and improvement gap of head and neck cancers in middle-aged and older adults from 1990 to 2021.PloS one · 2025Article
- Enhancing Head and Neck Tumor Segmentation in MRI: The Impact of Image Preprocessing and Model Ensembling.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOver the past decades, lots of advance have occurred in the prevention, diagnosis, and treatment of head and neck cancer (HNC). However, the contemporaneous incidence and survival trends, on the basis of population-based registry, have not been reported.
methodsThe HNC cancer cases were accessed from the Surveillance, Epidemiology, and End Results (SEER) database. The incidence trend was analyzed by joinpoint analysis, with the survival trend being analyzed by period analysis of relative survival rate (RSR) and Kaplan-Meier analyses. Cox regression analysis was performed to identify the prognostic factors for overall survival.
resultsThe general incidence trend of HNC increases slightly, with an average annual percentage change of 0.6%, along with five fluctuating segments. The improvement of net survival over the past decades was showed by increasing 60-month RSR, from 54.1% to 56.0% to 60.9% to 66.8%, which was further confirmed by Kaplan-Meier analyses. Moreover, disparities in incidence and survival patterns can be observed in different subgroups.
conclusionA fluctuating incidence pattern and an ever-improving survival were observed in HNC over time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.