Evidence map›Paper›PMID 34336366›Full record

ArticleLiver research (Beijing, China)2020

Adoptive transfer of

Xin Guo, Bilian Zhu, Hang Xu, Honggui Li, Boxiong Jiang, Yina Wang, Benrong Zheng, Shannon Glaser, Gianfranco Alpini, Chaodong Wu

Open access · goldAbstract read
In one paragraph

Article in Liver research (Beijing, China), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Xin GuoDepartment of Nutrition, Texas A&M University, College Station, TX, USA.
Bilian ZhuDepartment of Nutrition, Texas A&M University, College Station, TX, USA.
Hang XuDepartment of Nutrition, Texas A&M University, College Station, TX, USA.
Honggui LiDepartment of Nutrition, Texas A&M University, College Station, TX, USA.
Boxiong JiangDepartment of VIP Medical Service Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yina WangDepartment of VIP Medical Service Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Benrong ZhengDepartment of VIP Medical Service Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shannon GlaserMedical Physiology, Texas A&M University College of Medicine, Bryan, TX, USA.
Gianfranco AlpiniHepatology and Gastroenterology, Medicine, Indiana University, Indianapolis, IN, USA.
Chaodong WuDepartment of Nutrition, Texas A&M University, College Station, TX, USA.
Texas A&M University · USSun Yat-sen University · CNBryan College · USIndiana University – Purdue University Indianapolis · USThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

GROWTH REGULATION OF THE INTRAHEPATIC BILIARY TREER01DK054811 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2000 to 2021
$3.8M
Role of STING in Cholestatic Liver InjuryR01DK135881 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI Burcin Ekser, Shannon Stroud Glaser · 2023 to 2026
$1.9M
ADK Regulation of Fat Metabolism and Insulin SensitivityR01DK124854 · NIDDK · TEXAS A&M AGRILIFE RESEARCH · PI WU, CHAODONG · 2020 to 2023
$1.8M
Role of Sensory Neuropeptides in the Regulation of Biliary FunctionR01DK076898 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2008 to 2016
$1.8M
Protective role of adenosine 2A receptor in NAFLDR01DK095862 · NIDDK · TEXAS A&M AGRILIFE RESEARCH · PI WU, CHAODONG · 2013 to 2017
$1.6M
Metabolic regulation of adipocyte-macrophage crosstalk in obesityR01DK095828 · NIDDK · TEXAS A&M AGRILIFE RESEARCH · PI WU, CHAODONG · 2013 to 2016
$1.3M
Neuroendocrine Regulation of Biliary Growth and FibrosisR01DK110035 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2017 to 2020
$1.2M
REGULATION OF CELLULAR SENESCENCE BY NON-CODING RNAS IN ALCOHOLIC LIVER INJURYR21AA025997 · NIAAA · SCOTT AND WHITE MEMORIAL HOSPITAL · PI ALPINI, GIANFRANCO D, MENG, FANYIN · 2017 to 2018
$435k
BLRD VA I01 BX000574BLRD VA IK6 BX004601NIAAA NIH HHS R21 AA025997NIDDK NIH HHS R01 DK054811NIDDK NIH HHS R01 DK076898NIDDK NIH HHS R01 DK095828NIDDK NIH HHS R01 DK095862NIDDK NIH HHS R01 DK110035NIDDK NIH HHS R01 DK124854NIDDK NIH HHS R01 DK135881
6 · The paper itself

Abstract

BACKGROUND AND

objectivesHepatic steatosis and inflammation are key characteristics of non-alcoholic fatty liver disease (NAFLD). However, whether and how hepatic steatosis and liver inflammation are differentially regulated remains to be elucidated. Considering that disruption of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (

methods

resultsAfter the feeding period, HFD-fed

conclusions

Indexed as

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3/iPfk2)Hematopoietic cellsHepatic steatosisInflammationMacrophages

Identifiers

PMID34336366
PMCPMC8320599
OpenAlexW3083074662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.