Evidence map›Paper›PMID 34336299›Full record

ArticleCase reports in cardiology2021

Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient.

Vivek D Shah, Adeba Mohammad, Shuktika Nandkeolyar, Liset Stoletniy, Tahmeed Contractor

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Case Report: Two cases of recurrent syncope caused byFrontiers in cardiovascular medicine · 2026
    Article
  3. Cannabis-Induced Cardiac Arrest in a Young Adult: A Case Report.The American journal of case reports · 2025
    Article
  4. What We May not Know: Torsades de Pointes Induced by Cannabinoid Use.Journal of community hospital internal medicine perspectives · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vivek D ShahDepartment of Internal Medicine, Loma Linda University Medical Center, CA, USA.ORCID https://orcid.org/0000-0001-8976-6712
Adeba MohammadDepartment of Internal Medicine, Loma Linda University Medical Center, CA, USA.ORCID https://orcid.org/0000-0002-1754-0770
Shuktika NandkeolyarDepartment of Internal Medicine, Division of Cardiology, Loma Linda University Medical Center, CA, USA.ORCID https://orcid.org/0000-0003-3163-3698
Liset StoletniyDepartment of Internal Medicine, Division of Cardiology, Loma Linda University Medical Center, CA, USA.ORCID https://orcid.org/0000-0001-6113-2240
Tahmeed ContractorDepartment of Internal Medicine, Division of Cardiology, Loma Linda University Medical Center, CA, USA.ORCID https://orcid.org/0000-0001-8375-9300
Loma Linda University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are several recent reports of tetrahydrocannabinol vaping-related sudden cardiac arrest, and the mechanisms are unclear. We report a unique case of a 19-year-old female who suffered documented prolonged QTc leading to Torsades de pointes and cardiac arrest in the setting of frequent marijuana wax vaping. While she demonstrated normal baseline QTc measurements years earlier, she was found to have a genetic predisposition to QTc prolongation (genetic mutation, family history of prolonged QTc), suggesting that specific patient populations are at higher risk of these adverse events. The patient was acutely managed with isoproterenol to increase the heart rate and was discharged on nadolol after placement of an implantable cardioverter-defibrillator. Marijuana wax vaping and dabbing may cause fatal Torsades de pointes in susceptible patients, and further research is required to identify these patients a priori.

Identifiers

PMID34336299
PMCPMC8292089
OpenAlexW3189677047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.