Evidence map›Paper›PMID 34336281›Full record

ArticleTuberculosis research and treatment2021

Treatment Outcomes and Associated Factors in Tuberculosis Patients at Atwima Nwabiagya District, Ashanti Region, Ghana: A Ten-Year Retrospective Study.

Sadick Ahmed Agyare, Francis Adjei Osei, Samuel Frimpong Odoom, Nicholas Karikari Mensah, Ernest Amanor, Charles Martyn-Dickens, Michael Owusu-Ansah, Aliyu Mohammed, Eugene Osei Yeboah

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Article in Tuberculosis research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

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21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  20. A multiplex PCR assay for the differentiation ofFrontiers in cellular and infection microbiology · 2023
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Sadick Ahmed AgyareGhana Health Service, Atwima Nwabiagya, Ghana.
Francis Adjei OseiKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Samuel Frimpong OdoomKomfo Anokye Teaching Hospital, Kumasi, Ghana.ORCID https://orcid.org/0000-0001-8398-3898
Nicholas Karikari MensahKomfo Anokye Teaching Hospital, Kumasi, Ghana.
Ernest AmanorKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Charles Martyn-DickensKomfo Anokye Teaching Hospital, Kumasi, Ghana.
Michael Owusu-AnsahKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Aliyu MohammedKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Eugene Osei YeboahGhana Health Service, Zuarungu, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTuberculosis poses a great threat to public health around the globe and affects persons mostly in their productive age, notwithstanding; everyone is susceptible to tuberculosis (TB) infection. To assess the effectiveness and performance of the tuberculosis control program activities, the percentage of cases with treatment success outcome is key. To control tuberculosis, interrupting transmission through effective treatment cannot be overemphasized. The study was conducted to determine factors associated with TB treatment outcome, in the Atwima Nwabiagya District from 2007-2017.

methodA Retrospective review of routine/standard TB registers was carried out in five directly observed therapy short-course (DOTS) centres at the Atwima Nwabiagya District from January 2007 to December 2017. Demographic characteristics, clinical characteristics, and treatment outcomes were assessed. Bivariate and multivariate logistic regression was conducted to determine the predictors of successful treatment outcome.

resultsOf the 891 TB client's data that was assessed in the district, the treatment success rate was 68.46%. Patients, aged ≤ 20 years (adjusted odds ratio (aOR) = 4.74, 95%CI = 1.75 - 12.83) and 51-60 years (aOR = 1.94, 95%CI = 1.12 - 3.39), having a pretreatment weight of 35-45 kg (aOR = 2.54, 95%CI = 1.32 - 4.87), 46-55 kg (aOR = 2.75, 95%CI = 1.44 - 5.27) and 56-65 kg (aOR = 3.04, 95%CI = 1.50 - 6.14) were associated with treatment success. However, retreatment patients (aOR = 0.31, 95%CI = 0.11 - 0.84) resulted in unsuccessful treatment outcome.

conclusionSuccessful treatment outcome among TB patients was about 20.00% and 30.00% lower compared to the national average treatment success rate and WHO target, respectively. Active monitoring, motivation, and counselling of retreatment patients and patients with advanced age are key to treatment success.

Identifiers

PMID34336281
PMCPMC8315879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.