Evidence map›Paper›PMID 34336129›Full record

ArticleOxidative medicine and cellular longevity2021

Synergistic Antioxidant Effects of Araloside A and L-Ascorbic Acid on H

Yaqin Tian, Xiuling Zhang, Meiling Du, Fengfeng Li, Manyu Xiao, Wentao Zhang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Frontiers in microbiology · 2026
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  5. Review
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  9. Total cucurbitacins fromFrontiers in pharmacology · 2024
    Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yaqin TianCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.
Xiuling ZhangCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.ORCID https://orcid.org/0000-0001-7613-4687
Meiling DuCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.
Fengfeng LiCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.
Manyu XiaoCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.
Wentao ZhangCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China.ORCID https://orcid.org/0000-0001-7833-1342
Northeast Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Araloside A is a pentacyclic triterpenoid saponin, and L-ascorbic acid is a globally recognized antioxidant. In this study, coadministered araloside A and L-ascorbic acid were found to have a strong synergistic antioxidant effect, and correlations between cellular antioxidant indexes and free radical scavenging ability were found. Individual and combined pretreatment with araloside A and L-ascorbic acid increased both cell viability and antioxidant enzyme activity and inhibited the release of lactate dehydrogenase (LDH); the accumulation of malondialdehyde (MDA), lipid peroxidation (LPO) products, and H

Indexed as

AntioxidantsAscorbic AcidDrugs, Chinese HerbalHEK293 CellsHumansHydrogen PeroxideOleanolic AcidOxidative StressSaponinsAntioxidantsaraloside AAscorbic AcidDrugs, Chinese HerbalHydrogen PeroxideOleanolic AcidSaponins

Identifiers

PMID34336129
PMCPMC8289608
OpenAlexW3177964663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.