Evidence map›Paper›PMID 34336105›Full record

ArticleOxidative medicine and cellular longevity2021

Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H

Qing Zhang, Ruo-Lan Li, Ting Tao, Jia-Yi Sun, Jia Liu, Ting Zhang, Wei Peng, Chun-Jie Wu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Anti-Inflammatory and AntioxidativeMolecules (Basel, Switzerland) · 2024
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  15. Essential oil from the roots ofFrontiers in pharmacology · 2022
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  16. Frontiers in pharmacology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qing ZhangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0002-0152-6552
Ruo-Lan LiSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0002-0110-1095
Ting TaoSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0001-5345-5592
Jia-Yi SunInnovation Research Institute, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.ORCID https://orcid.org/0000-0002-1987-4512
Jia LiuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0001-7495-9167
Ting ZhangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0001-5571-9723
Wei PengSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0003-0511-9564
Chun-Jie WuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China.ORCID https://orcid.org/0000-0001-7496-8469
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cicadae Periostracum (CPM), a commonly used animal traditional Chinese medicine (TCM), possesses antifebrile, spasmolytic, antiasthmatic, and antiphlogistic effects. In our present paper, we aimed to systemically investigate the antiepileptic effects of CPM in epileptic mice and explore the related molecular mechanism. Pentylenetetrazole- (PTZ) and strychnine-induced convulsion mice were established, and the results showed CPM could prolong the latency of convulsion and death and improve the neuronal damage in the hippocampus of PTZ-induced mice. Furthermore, the H

Indexed as

AnimalsAnticonvulsantsApoptosisHemipteraInsectaMiceNF-E2-Related Factor 2PC12 CellsPhosphatidylinositol 3-KinasesRatsSignal TransductionAnticonvulsantsNF-E2-Related Factor 2Phosphatidylinositol 3-Kinases

Identifiers

PMID34336105
PMCPMC8324375
OpenAlexW3186355934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.