Evidence map›Paper›PMID 34336089›Full record

ReviewOxidative medicine and cellular longevity2021

Genistein: An Integrative Overview of Its Mode of Action, Pharmacological Properties, and Health Benefits.

Javad Sharifi-Rad, Cristina Quispe, Muhammad Imran, Abdur Rauf, Muhammad Nadeem, Tanweer Aslam Gondal, Bashir Ahmad, Muhammad Atif, Mohammad S Mubarak, Oksana Sytar and 14 more

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 185 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
185citing papers in PubMed, 5 pooled it
33.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

185 citing papers in PubMed, 5 syntheses or guidelines pooled it, 356 citations in OpenAlex.

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  6. Effect of AG1Frontiers in nutrition · 2026
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125 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 18 institutions in 15 countries.

Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-7301-8151
Cristina QuispeFacultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique 1110939, Chile.
Muhammad ImranUniversity Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan.
Abdur RaufDepartment of Chemistry, University of Swabi, Anbar-, 23561 Khyber Pakhtunkhwa, Pakistan.ORCID https://orcid.org/0000-0003-2429-5491
Muhammad NadeemDepartment of Environmental Sciences, COMSATS Institute of Information Technology, Vehari-, Pakistan.
Tanweer Aslam GondalSchool of Exercise and Nutrition, Deakin University, Victoria 3125, Australia.
Bashir AhmadCenter of Biotechnology and Microbiology, University of Peshawar, Peshawar-, 25120 KPK, Pakistan.
Muhammad AtifDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72341, Saudi Arabia.ORCID https://orcid.org/0000-0002-8921-4376
Mohammad S MubarakDepartment of Chemistry, The University of Jordan, Amman 11942, Jordan.
Oksana SytarDepartment of Plant Biology Department, Institute of Biology, Taras Shevchenko National University of Kyiv, Volodymyrska Str., 64, Kyiv 01033, Ukraine.
Oxana Mihailovna ZhilinaDepartment of Organic Chemistry, Pyatigorsk Medical-Pharmaceutical Institute (PMPI), Branch of Volgograd State Medical University, Ministry of Health of Russia, Pyatigorsk 357532, Russia.
Ekaterina Robertovna GarsiyaDepartment of Pharmacognosy, Botany and Technology of Phytopreparations, Pyatigorsk Medical-Pharmaceutical Institute (PMPI), Branch of Volgograd State Medical University, Ministry of Health of Russia, Pyatigorsk 357532, Russia.ORCID https://orcid.org/0000-0003-3217-0680
Antonella SmeriglioDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.
Domenico TrombettaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.
Daniel Gabriel PonsGrupo Multidisciplinar de Oncología Traslacional (GMOT), Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Universitat de les Illes Balears (UIB), Instituto de Investigación Sanitaria Illes Balears (IdISBa), Palma 07122, Spain.
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepción, Concepción 4070386, Chile.ORCID https://orcid.org/0000-0003-3183-7623
Susana M CardosoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Ahmad Faizal Abdull RazisDepartment of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.ORCID https://orcid.org/0000-0001-9205-3764
Usman SunusiNatural Medicines and Products Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Ramla Muhammad KamalNatural Medicines and Products Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Lia Sanda RotariuBanat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Romania.ORCID https://orcid.org/0000-0002-4561-5039
Monica ButnariuBanat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Romania.ORCID https://orcid.org/0000-0002-2032-5000
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID https://orcid.org/0000-0002-1523-9116
Universiti Putra Malaysia · MYUniversity of Medicine and Pharmacy of Craiova · ROUniversity of Messina · ITUnivesity of Life Science "King Mihai I" from Timisoara · ROVolgograd State Medical University · RUArturo Prat University · CLCOMSATS University Islamabad · PKDeakin University · AUJouf University · SARede de Química e Tecnologia · PTServei de Salut de les Illes Balears · ESShahid Beheshti University of Medical Sciences · IRSlovak University of Agriculture in Nitra · SKUniversity of Concepción · CLUniversity of Jordan · JOUniversity of Lahore · PKUniversity of Peshawar · PKUniversity of Swabi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genistein is an isoflavone first isolated from the brooming plant Dyer's

Indexed as

Anticarcinogenic AgentsGenisteinHumansAnticarcinogenic AgentsGenistein

Identifiers

PMID34336089
PMCPMC8315847
OpenAlexW3191712277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.