Evidence map›Paper›PMID 34335978›Full record

SynthesisTheranostics2021

Radiomics in prostate cancer imaging for a personalized treatment approach - current aspects of methodology and a systematic review on validated studies.

Simon K B Spohn, Alisa S Bettermann, Fabian Bamberg, Matthias Benndorf, Michael Mix, Nils H Nicolay, Tobias Fechter, Tobias Hölscher, Radu Grosu, Arturo Chiti and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Delta radiomics: a systematic review.La Radiologia medica · 2021
    Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. The value of habitat analysis based onBMC medical imaging · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Deep learning based automated delineation of the intraprostatic gross tumour volume in PSMA-PET for patients with primary prostate cancer.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Simon K B SpohnDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Alisa S BettermannDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Fabian BambergDepartment of Radiology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Matthias BenndorfDepartment of Radiology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Michael MixDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Nils H NicolayDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Tobias FechterDepartment of Radiation Oncology - Division of Medical Physics, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Tobias HölscherRadiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden.
Radu GrosuInstitute of Computer Engineering, Vienne University of Technology, Vienna, Austria.
Arturo ChitiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele - Milan, Italy.
Anca L GrosuDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
Constantinos ZamboglouDepartment of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine. University of Freiburg, Germany.
University of Freiburg · DEUniversity Medical Center Freiburg · DEDeutschen Konsortium für Translationale Krebsforschung · DEGerman Cancer Research Center · DEHelmholtz-Zentrum Dresden-Rossendorf · DEHumanitas University · ITTU Wien · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is one of the most frequently diagnosed malignancies of men in the world. Due to a variety of treatment options in different risk groups, proper diagnostic and risk stratification is pivotal in treatment of PCa. The development of precise medical imaging procedures simultaneously to improvements in big data analysis has led to the establishment of radiomics - a computer-based method of extracting and analyzing image features quantitatively. This approach bears the potential to assess and improve PCa detection, tissue characterization and clinical outcome prediction. This article gives an overview on the current aspects of methodology and systematically reviews available literature on radiomics in PCa patients, showing its potential for personalized therapy approaches. The qualitative synthesis includes all imaging modalities and focuses on validated studies, putting forward future directions.

Indexed as

Diagnostic ImagingHumansImage Processing, Computer-AssistedMalePrecision MedicineProstatic Neoplasms

Identifiers

PMID34335978
PMCPMC8315055
OpenAlexW3186867303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.