Evidence map›Paper›PMID 34335974›Full record

ArticleTheranostics2021

Environmentally-induced

Qian Zhang, Priya Wadgaonkar, Liping Xu, Chitra Thakur, Yao Fu, Zhuoyue Bi, Yiran Qiu, Bandar Almutairy, Wenxuan Zhang, Paul Stemmer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs.International journal of molecular sciences · 2022
    Review
  6. Article
  7. JMJD family proteins in cancer and inflammation.Signal transduction and targeted therapy · 2022
    Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qian ZhangDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Priya WadgaonkarDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Liping XuDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Chitra ThakurDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Yao FuDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Zhuoyue BiDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Yiran QiuDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Bandar AlmutairyDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Wenxuan ZhangDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Paul StemmerDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Fei ChenDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Wayne State University · USEugene Applebaum College of Pharmacy and Health Sciences · US

Funding

Reduced Reactive Oxygen Species and Oxidative Phosphorylation in Arsenic-Induced Cancer Stem CellsR01ES028263 · NIEHS · WAYNE STATE UNIVERSITY · PI CHEN, FEI · 2017 to 2021
$1.9M
Dissecting Nrf2-dependent HIF1a activation mechanism in arsenic-induced cancer stem-like cellsR01ES031822 · NIEHS · WAYNE STATE UNIVERSITY · PI CHEN, FEI · 2021 to 2025
$1.8M
Arsenic-Induced miRNA-199 and mriRNA-214 Deplete Mitochondrial DNA for the Generation of Cancer Stem-Like CellsR01ES028335 · NIEHS · WAYNE STATE UNIVERSITY · PI CHEN, FEI · 2018 to 2022
$1.3M
NIEHS NIH HHS R01 ES028263NIEHS NIH HHS R01 ES028335NIEHS NIH HHS R01 ES031822
6 · The paper itself

Abstract

The novel β-coronavirus, SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), has infected more than 177 million people and resulted in 3.84 million death worldwide. Recent epidemiological studies suggested that some environmental factors, such as air pollution, might be the important contributors to the mortality of COVID-19. However, how environmental exposure enhances the severity of COVID-19 remains to be fully understood. In the present report, we provided evidence showing that

Indexed as

Alveolar Epithelial CellsAnimalsCathepsinsCell LineCells, CulturedCOVID-19DioxygenasesEnvironmental ExposureHistone DemethylasesHistonesHumansNeuropilin-1Nuclear ProteinsPandemicsPolysaccharidesRatsCathepsinsDioxygenasesHistone DemethylasesHistonesNeuropilin-1Nuclear ProteinsPolysaccharidesRIOX2 protein, humanSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19GlycosylationmdigNRP1NRP2

Identifiers

PMID34335974
PMCPMC8315075
OpenAlexW3184770315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.