Evidence map›Paper›PMID 34335967›Full record

ArticleTheranostics2021

MicroRNA-185-5p inhibits hepatic gluconeogenesis and reduces fasting blood glucose levels by suppressing G6Pase.

Hui Zheng, Jian Wan, Yi Shan, Xi Song, Jie Jin, Qing Su, Song Chen, Xinyuan Lu, Jialin Yang, Quanmin Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Epigenetic Regulation of DAPK1 and Netrin-1 Drives Diabetic Encephalopathy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Article
  3. Biology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Accelerated Wound Healing in Diabetic Rat by miRNA-185-5p and Its Anti-Inflammatory Activity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  12. Review
  13. Polyphenol fromFoods (Basel, Switzerland) · 2022
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Hui ZhengMedical College of Soochow University, Suzhou, Jiangsu; PLA Rocket Force Characteristic Medical Center, Beijing, China.
Jian WanDepartment of Emergency and Critical Care Medicine, Shanghai Pudong New Area People's Hospital, Shanghai University of Medicine and Health Sciences, Shanghai 201299, China.
Yi ShanDepartment of Emergency and ICU, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Xi SongDepartment of Emergency and Critical Care Medicine, Shanghai Pudong New Area People's Hospital, Shanghai University of Medicine and Health Sciences, Shanghai 201299, China.
Jie JinDepartment of Endocrinology and Metabolic Diseases, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Qing SuDepartment of Endocrinology and Metabolic Diseases, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Song ChenDepartment of Emergency and Critical Care Medicine, Shanghai Pudong New Area People's Hospital, Shanghai University of Medicine and Health Sciences, Shanghai 201299, China.
Xinyuan LuDepartment of Emergency and Critical Care Medicine, Shanghai Pudong New Area People's Hospital, Shanghai University of Medicine and Health Sciences, Shanghai 201299, China.
Jialin YangDepartment of Endocrinology and Metabolic Diseases, Minhang Hospital, Fudan University, Shanghai 201100, China.
Quanmin LiMedical College of Soochow University, Suzhou, Jiangsu; PLA Rocket Force Characteristic Medical Center, Beijing, China.
Yuping SongDepartment of Endocrinology and Metabolic Diseases, Minhang Hospital, Fudan University, Shanghai 201100, China.
Bo LiDepartment of Endocrinology and Metabolic Diseases, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Shanghai University of Medicine and Health Sciences · CNFudan University · CNMinhang District Central Hospital · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3' Untranslated RegionsAnimalsBlood GlucoseDiabetes Mellitus, Type 2Diet, High-FatDisease Models, AnimalFemaleGluconeogenesisGlucoseGlucose-6-PhosphataseHyperglycemiaInsulinInsulin ResistanceLiverMaleMice3' Untranslated RegionsBlood GlucoseGlucoseGlucose-6-PhosphataseInsulinMicroRNAsMirn185 microRNA, mousehepatic gluconeogenesishyperglycemiametforminmiR-185-5pType 2 diabetes

Identifiers

PMID34335967
PMCPMC8315058
OpenAlexW3184397719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.