Evidence map›Paper›PMID 34335958›Full record

ArticleTheranostics2021

Attenuation of tonic inhibition prevents chronic neurovascular impairments in a Thy1-ChR2 mouse model of repeated, mild traumatic brain injury.

James R Mester, Paolo Bazzigaluppi, Adrienne Dorr, Tina Beckett, Matthew Burke, JoAnne McLaurin, John G Sled, Bojana Stefanovic

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Persistent dysmorphology and dysfunction of the brain microvasculature following repeated trauma.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  3. Article
  4. Article
  5. Cellular senescence in brain aging and cognitive decline.Frontiers in aging neuroscience · 2023
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

James R MesterUniversity of Toronto, Department of Medical Biophysics, Toronto, Ontario, Canada.
Paolo BazzigaluppiPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Adrienne DorrPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Tina BeckettPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Matthew BurkeNeuropsychiatry Program, Department of Psychiatry and Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
JoAnne McLaurinBiological Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
John G SledUniversity of Toronto, Department of Medical Biophysics, Toronto, Ontario, Canada.
Bojana StefanovicUniversity of Toronto, Department of Medical Biophysics, Toronto, Ontario, Canada.
Sunnybrook Health Science Centre · CASunnybrook Research InstituteUniversity of Toronto · CAHealth Sciences Centre · CASunnybrook Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrainBrain ConcussionDisease Models, AnimalFemaleMaleMiceMice, Inbred StrainsMicroscopy, FluorescenceNeuronsNeurovascular CouplingOptogenetics708L-655Neurovascular couplingOptogeneticsTraumatic brain injuryTwo-photon fluorescence microscopy

Identifiers

PMID34335958
PMCPMC8315057
OpenAlexW3174746207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.