Evidence map›Paper›PMID 34335957›Full record

ArticleTheranostics2021

Snail1 expression in endothelial cells controls growth, angiogenesis and differentiation of breast tumors.

David Cabrerizo-Granados, Raúl Peña, Laura Palacios, Laura Carrillo-Bosch, Josep Lloreta-Trull, Laura Comerma, Mar Iglesias, Antonio García de Herreros

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

David Cabrerizo-GranadosPrograma de Recerca en Càncer, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Unidad Asociada al CSIC, Barcelona, Spain.
Raúl PeñaPrograma de Recerca en Càncer, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Unidad Asociada al CSIC, Barcelona, Spain.
Laura PalaciosPrograma de Recerca en Càncer, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Unidad Asociada al CSIC, Barcelona, Spain.
Laura Carrillo-BoschPrograma de Recerca en Càncer, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Unidad Asociada al CSIC, Barcelona, Spain.
Josep Lloreta-TrullDepartament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
Laura ComermaServei d'Anatomia Patològica, Hospital del Mar, Barcelona, Spain.
Mar IglesiasServei d'Anatomia Patològica, Hospital del Mar, Barcelona, Spain.
Antonio García de HerrerosPrograma de Recerca en Càncer, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Unidad Asociada al CSIC, Barcelona, Spain.
Hospital Del Mar · ESPompeu Fabra University · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snail1 is a transcriptional factor required for epithelial to mesenchymal transition and activation of cancer-associated fibroblasts (CAF). Apart from that, tumor endothelial cells also express Snail1. Here, we have unraveled the role of Snail1 in this tissue in a tumorigenic context.

Indexed as

AnimalsBreast NeoplasmsCancer-Associated FibroblastsCarcinogenesisCell Line, TumorEndothelial CellsEpithelial-Mesenchymal TransitionFemaleFibroblastsHumansMiceMice, Inbred C57BLMice, TransgenicNeovascularization, PathologicSnail Family Transcription FactorsTranscription FactorsSNAI1 protein, humanSnail Family Transcription FactorsTranscription Factors

Identifiers

PMID34335957
PMCPMC8315050
OpenAlexW3174079058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.