Evidence map›Paper›PMID 34335823›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

The Success of Topical Treatment of Onychomycosis Seems to Be Influenced by Fungal Features.

Vanessa Vasconcellos-Pontello, Flávia Franco Veiga, Marina Cristina Gadelha, Marielen Ribeiro, Melyssa Negri, Terezinha Inez Estivalet Svidzinski

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Case of Mixed Infection of Toenail Caused byJournal of fungi (Basel, Switzerland) · 2023
    Article
  2. Efficacy of Propolis Gel on Mature Biofilm Formed byJournal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vanessa Vasconcellos-PontelloDepartamento de Análises Clínicas e Biomedicina, Centro de Ciências da Saúde, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.
Flávia Franco VeigaDepartamento de Análises Clínicas e Biomedicina, Centro de Ciências da Saúde, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.ORCID https://orcid.org/0000-0001-5562-0811
Marina Cristina GadelhaDepartamento de Análises Clínicas e Biomedicina, Centro de Ciências da Saúde, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.
Marielen RibeiroDepartamento de Análises Clínicas e Biomedicina, Centro de Ciências da Saúde, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.ORCID https://orcid.org/0000-0001-8197-0321
Melyssa NegriDepartamento de Análises Clínicas e Biomedicina, Centro de Ciências da Saúde, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.ORCID https://orcid.org/0000-0003-2071-8872
Terezinha Inez Estivalet SvidzinskiDepartamento de Análises Clínicas e Biomedicina, Centro de Ciências da Saúde, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.ORCID https://orcid.org/0000-0003-2525-9046
Universidade Estadual de Maringá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the topical treatment of onychomycosis using a 10% hydroalcoholic propolis extract (PE) in two aleatorily chosen patients and analyze possible risk factors from hosts including some particularities of the isolated fungi that may justify the outcomes achieved. MATERIALS AND

methodsA topical treatment, with PE, was started in two cases of toe onychomycosis due to

resultsWithin four months, both patients showed evident improvement, but with different outcomes. The possible host-related risk factors justifying the poorer outcome in patient 1 include a longer duration time of onychomycosis (50 years). Some particularities in the

conclusionsA partial clinical and complete mycological cure for the two patients was achieved after four months of PE daily use. Despite a complete recovery, a different outcome was observed between both cases. A more persistent onychomycosis, added to greater fungal potential to produce biofilm on the nail, seems to influence greatly the success of a topical treatment with PE.

Identifiers

PMID34335823
PMCPMC8286179
OpenAlexW3179809190

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.